Continuous EEG monitoring in Kenyan children with non-traumatic coma.

Archives of Disease in Childhood
Samson GwerC R Newton

Abstract

The aim of this study was to describe the EEG and clinical profile of seizures in children with non-traumatic coma, compare seizure detection by clinical observations with that by continuous EEG, and relate EEG features to outcome. This prospective observational study was conducted at the paediatric high dependency unit of Kilifi District Hospital, Kenya. Children aged 9 months to 13 years presenting with acute coma were monitored by EEG for 72 h or until they regained consciousness or died. Poor outcome was defined as death or gross motor deficits at discharge. 82 children (median age 2.8 (IQR 2.0-3.9) years) were recruited. An initial medium EEG amplitude (100-300 mV) was associated with less risk of poor outcome compared to low amplitude (≤100 mV) (OR 0.2, 95% CI 0.1 to 0.7; p<0.01). 363 seizures in 28 (34%) children were observed: 240 (66%) were electrographic and 112 (31%) electroclinical. In 16 (20%) children, electrographic seizures were the only seizure types detected. The majority (63%) of electroclinical seizures had focal clinical features but appeared as generalised (79%) or focal with secondary generalisation (14%) on EEG. Occurrence of any seizure or status epilepticus during monitoring was associated with poor ou...Continue Reading

References

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Citations

Jan 22, 2013·Current Neurology and Neuroscience Reports·Nicholas S AbendUNKNOWN Pediatric Critical Care EEG Group (PCCEG) and the Critical Care EEG Monitoring Research Consortium (CCEMRC)
Aug 6, 2013·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Alyssa D PensirikulNicholas S Abend
Sep 5, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Symon M KariukiUNKNOWN SEEDS investigators
Apr 25, 2015·Epilepsy & Behavior : E&B·Nicholas S AbendDennis J Dlugos
Apr 26, 2013·Epilepsia·Symon M KariukiCharles R J C Newton
May 15, 2018·Journal of Child Neurology·Iván Sánchez FernándezTobias Loddenkemper
Aug 13, 2013·Paediatrics and International Child Health·Samson GwerRichard Idro
Jan 30, 2015·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Susan T HermanUNKNOWN Critical Care Continuous EEG Task Force of the American Clinical Neurophysiology Society
Sep 7, 2019·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Hae Young BaangOlga Taraschenko
Jan 30, 2015·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Nicholas S AbendSankey Williams
Jun 10, 2015·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Nicholas S AbendSankey Williams
Sep 29, 2020·Journal of Epilepsy Research·Modibo SangareGordon A Awandare
Sep 6, 2020·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·France W Fung, Nicholas S Abend
Mar 15, 2021·Seizure : the Journal of the British Epilepsy Association·Jian HuRui Xiao
Apr 25, 2021·Neurology·France W FungNicholas S Abend

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