PMID: 3767038Oct 1, 1986Paper

Continuous-flow apneic ventilation during thoracotomy

Anesthesiology
M F BabinskiL Bunegin

Abstract

Continuous-flow apneic ventilation (CFAV) by endobronchial insufflation of conditioned gas was evaluated in dogs during thoracotomy. In Group 1 (n = 6), dogs were anesthetized with pentobarbital (25 mg/kg). An endobronchial catheter (2.5 mm ID) was introduced into each mainstem bronchus using a fiberoptic bronchoscope and held in place by an endotracheal tube. Before the onset of CFAV (total flow 1.01 X kg-1 X min-1, the animals were paralyzed with pancuronium bromide and muscle relaxation was monitored with a peripheral nerve stimulator. The CFAV delivery system consisted of a flow meter, air/oxygen blender, oxygen analyzer, heated humidifier, and ultrasonic spirometer. Blood gas values were measured after 30 min of spontaneous ventilation, and CFAV with: 1) closed chest, fractional inspired O2 concentration (FIO2) 0.21; 2) open chest, FIO2 0.21; 3) open chest, FIO2 0.21, continuous positive airway pressure (CPAP) 5 mmHg; and 4) open chest FIO2 0.4, CPAP 5 mmHg. This last combination resulted in a mean PaO2 of 113.1 +/- 5.5 (SEM) mmHg and a PaCO2 of 35.0 +/- 2.1 (SEM) mmHg. In Group 2 (n = 6), animals with open chests were ventilated with CFAV (FIO2 0.4 and CPAP 5 mmHg) for 5 h. Adequate oxygenation and ventilation were achiev...Continue Reading

Citations

Apr 1, 1990·Acta Anaesthesiologica Scandinavica·T HachenbergM Wendt
Oct 1, 1989·Journal of Cardiothoracic Anesthesia·H B HowellD Harders
Nov 1, 1988·Acta Anaesthesiologica Scandinavica·L BuneginR B Smith
Nov 18, 2005·The American Journal of Emergency Medicine·William J MeggsTimothy J Reeder
Mar 15, 2014·Anesteziologiia i reanimatologiia·A V AlekseevD S Fedorov

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