PMID: 7776356Sep 1, 1994

Continuous measurement of blood gases using a combined electrochemical and spectrophotometric sensor

Journal of Medical Engineering & Technology
B VenkateshS P Hendry


The use of a combined electrochemical and fibreoptic continuous intra-arterial blood gas sensor is described. The purpose of the study was to evaluate the performance of the sensor in 10 patients in the intensive therapy unit following insertion through a femoral arterial cannula. To our knowledge this is the first published study on the valuation of an intravascular blood gas sensor through a femoral arterial cannula. A total of 71 sets of data comparing the sensor with the blood gas analyser were obtained. The bias and precision for pH, PCO2 and PO2 were 0.006 and 0.07 pH units, 0.2 and 1.65 kPa (4.6% and 29%) and 0.8 and 2.7 kPa (5.1% and 14.3%) respectively. There was a degree of imprecision of the PCO2 sensor, the reasons for which are discussed. In summary, the intra-arterial sensor functioned well when inserted into the femoral artery in post-cardiopulmonary bypass patients. There were no complications attributable to sensor placement.


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Apr 1, 1989·British Journal of Anaesthesia·C J WilkinsC D Hanning
May 1, 1989·Critical Care Medicine·B A ShapiroW T Peruzzi
Feb 1, 1986·IEEE Transactions on Bio-medical Engineering·J L GehrichM Yafuso
Jan 1, 1981·Intensive Care Medicine·S V RithaliaJ Tinker
Feb 1, 1994·Critical Care Medicine·J L Vincent
Apr 1, 1993·Critical Care Medicine·J L Zimmerman, R P Dellinger


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Related Concepts

Blood Gas Analysis
Carbon Dioxide
Cardiopulmonary Bypass
Peripheral Venous Catheterization
Medical Device Design
Structure of Femoral Artery
Fiber Optic Technology
Hydrogen-Ion Concentration
Monitoring, Physiologic

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