PMID: 640915Apr 1, 1978Paper

Continuous measurement of gas partial pressures in intracerebral tissue

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
J Seylaz, E Pinard

Abstract

A mass spectrograph technique has been developed for measurement of physiological gas partial pressures locally in the brain. The sampling cannula is implanted stereotaxically and remains in situ for several weeks. It is a thin cylinder in shape, and is covered with a thin polyethylene membrane across which gas molecules can be sampled continuously. The conductance of this membrane is well adapted to the limited rate of replacement of gas molecules afforded by the cerebral tissue, hence there is no depletion around the cannula; this depletion has until now been the major problem of this technology. The present technique provides a continuous measurement with fast response time, which is directly proportional to the partial pressures of the gases. The variations can be expressed as a percentage of the base-line value.

Citations

Jul 1, 1981·Journal of Physics E: Scientific Instruments·C E Hahn
Jul 1, 1994·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A S Rigaud-MonnetJ Seylaz
Oct 26, 2018·Physiological Reviews·Thomas P Keeley, Giovanni E Mann
Jun 21, 1978·Pflügers Archiv : European journal of physiology·E Pinard, J Seylaz
Feb 1, 1987·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·C E Hahn
Jun 1, 2007·Antioxidants & Redox Signaling·Obinna Ndubuizu, Joseph C LaManna
Mar 13, 2019·International Journal of Molecular Sciences·Cristina Mas-BarguesConsuelo Borrás
Nov 24, 2001·Respiration Physiology·M Erecińska, I A Silver
Sep 23, 2003·Mechanisms of Ageing and Development·J-C Massabuau
Apr 4, 2006·Respiratory Physiology & Neurobiology·Timothy J Bradley

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