Continuous measures of driving performance on an advanced office-based driving simulator can be used to predict simulator task failure in patients with obstructive sleep apnoea syndrome

Thorax
Dipansu GhoshMark W Elliott

Abstract

Some patients with obstructive sleep apnoea syndrome are at higher risk of being involved in road traffic accidents. It has not been possible to identify this group from clinical and polysomnographic information or using simple simulators. We explore the possibility of identifying this group from variables generated in an advanced PC-based driving simulator. All patients performed a 90 km motorway driving simulation. Two events were programmed to trigger evasive actions, one subtle and an alert driver should not crash, while for the other, even a fully alert driver might crash. Simulator parameters including standard deviation of lane position (SDLP) and reaction times at the veer event (VeerRT) were recorded. There were three possible outcomes: 'fail', 'indeterminate' and 'pass'. An exploratory study identified the simulator parameters predicting a 'fail' by regression analysis and this was then validated prospectively. 72 patients were included in the exploratory phase and 133 patients in the validation phase. 65 (32%) patients completed the run without any incidents, 45 (22%) failed, 95 (46%) were indeterminate. Prediction models using SDLP and VeerRT could predict 'fails' with a sensitivity of 82% and specificity of 96%. Th...Continue Reading

Citations

Jan 18, 2014·Epilepsy & Behavior : E&B·William C ChenHal Blumenfeld
Mar 21, 2015·Traffic Injury Prevention·Charles M FarmerFeng Guo
Jan 29, 2013·Chronic Respiratory Disease·Antonio Sanna
Jan 16, 2018·F1000Research·Maria Bonsignore
Oct 13, 2016·ERJ Open Research·Dipansu GhoshMark W Elliott
Mar 21, 2020·Breathe·Sophia E Schiza, Izolde Bouloukaki
Oct 24, 2019·Sleep Medicine Clinics·Akshay Dwarakanath, Mark W Elliott
Oct 4, 2020·The European Respiratory Journal·Maria R BonsignoreWalter T McNicholas
Jun 9, 2020·Journal of Cardiac Failure·David B Carr, Brian R Ott
Jul 31, 2021·Sleep Medicine Clinics·Walter T McNicholas

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