Continuous positive air pressure improves orthonasal olfactory function of patients with obstructive sleep apnea

Sleep Medicine
Ute Walliczek-DworschakThomas Hummel

Abstract

Recent studies have suggested that patients with obstructive sleep apnea (OSA) might be affected by olfactory impairment. However, more evidence is needed on the effect that OSA has on the chemical senses (olfaction and gustatory) of these patients, and whether continuous positive airway pressure (CPAP) treatment might help to reverse possible impairment. A prospective study was conducted with 44 OSA patients (17 female and 27 male, mean age 54 ± 9.9 years) who were diagnosed via polysomnography and eligible for CPAP treatment. Orthonasal olfactory and gustatory function was measured with the extended Sniffin' Sticks test battery and "taste strips," respectively, before and after CPAP treatment. Baseline olfaction was decreased in OSA patients and after CPAP therapy olfactory scores (odor threshold-discrimination-identification score [TDI]: baseline 29.4 ± 4.11 after CPAP 32.3 ± 4.82; p = 0.001; odor threshold [THR]: baseline 5.28 ± 1.69 after CPAP 6.78 ± 2.61; p = 0.000; odor identification [ID]: baseline 12.9 ± 1.95 after CPAP 13.6 ± 1.33; p = 0.013) improved significantly. In contrast, neither baseline taste function in OSA patients nor gustatory function after treatment seemed to be affected. Orthonasal olfactory function i...Continue Reading

Citations

Feb 9, 2020·Sleep & Breathing = Schlaf & Atmung·Yifan LiuYongxiang Wei
Oct 1, 2019·Ear, Nose, & Throat Journal·Kerem Sami KayaBerna Uslu Coskun
Jul 5, 2019·Sleep & Breathing = Schlaf & Atmung·Ayse Secil DincSelma Fırat
Dec 18, 2019·Sleep & Breathing = Schlaf & Atmung·Süleyman Emre KarakurtHacı Hüseyin Dere
Aug 24, 2020·Journal of the Academy of Nutrition and Dietetics·Yun GaoXiang Gao

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