Continuous Positive Airway Pressure Treatment Increases Serum Vitamin D Levels in Male Patients with Obstructive Sleep Apnea

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine
Claudio LiguoriFabio Placidi

Abstract

Recent studies report a link between obstructive sleep apnea (OSA) syndrome, low vitamin D levels, and high parathyroid hormone (PTH) concentrations. The aim of the current study is to evaluate the effect of 7-night continuous positive airway pressure (CPAP) therapy on serum vitamin D, PTH, and calcium levels in patients with severe OSA syndrome. Patients with severe OSA were enrolled into the study and compared to control subjects. Patients with OSA underwent CPAP therapy for 7 nights and were consequently divided into responders (OSA-R, mean residual AHI < 5/h) and nonresponders (OSA-nR, mean residual AHI > 5/h). Serum vitamin D, PTH, and calcium levels were measured at baseline in patients with severe OSA (apnea-hypopnea index > 30/h) and control subjects. Patients with OSA underwent a final morning blood sample after 7-night CPAP therapy. We enrolled 90 patients with OSA into the study (65 OSA-R and 25 OSA-nR) compared to 32 control subjects. At baseline, lower vitamin D and higher PTH levels were detected in the OSA group compared to controls. After 7-night CPAP therapy, male OSA-R patients showed a significant increase in vitamin D levels. Conversely, female OSA-R patients did not show the same increase in vitamin D level...Continue Reading

Citations

Jul 17, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Baha Al-ShawwaDavid G Ingram
Jul 11, 2020·Sleep & Breathing = Schlaf & Atmung·Izolde BouloukakiSophia Schiza
Aug 3, 2020·Sleep & Breathing = Schlaf & Atmung·Dimitra I SiachpazidouKonstantinos I Gourgoulianis
Apr 2, 2019·JDR Clinical and Translational Research·H EimarC Flores-Mir
May 17, 2019·Rejuvenation Research·Judit PákóAndrás Bikov
Sep 29, 2020·Curēus·Philip C NwabuforSamson O Oyibo
Nov 3, 2020·Food Science & Nutrition·Shoumeng YanWeiwei Cui
Aug 12, 2021·Scientific Reports·Adam Domonkos TarnokiAndras Bikov
Nov 9, 2021·Expert Review of Molecular Diagnostics·Sartaj KhuranaSudeep Bose

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.