Abstract
Noninvasive continuous positive airway pressure (CPAP) is usually applied with a nasal or facial mask to treat mild acute respiratory failure (ARF) in infants. A pediatric helmet has now been introduced in clinical practice to deliver CPAP. This study compared treatment failure rates during CPAP delivered by helmet or facial mask in infants with respiratory syncytial virus-induced ARF. In this multicenter randomized controlled trial, 30 infants with respiratory syncytial virus-induced ARF were randomized to receive CPAP by helmet (n = 17) or facial mask (n = 13). The primary endpoint was treatment failure rate (defined as due to intolerance or need for intubation). Secondary outcomes were CPAP application time, number of patients requiring sedation, and complications with each interface. Compared with the facial mask, CPAP by helmet had a lower treatment failure rate due to intolerance (3/17 [17%] vs 7/13 [54%], P = .009), and fewer infants required sedation (6/17 [35%] vs 13/13 [100%], P = .023); the intubation rates were similar. In successfully treated patients, CPAP resulted in better gas exchange and breathing pattern with both interfaces. No major complications due to the interfaces occurred, but CPAP by mask had higher r...Continue Reading
Citations
Dec 10, 2015·Current Opinion in Critical Care·Giorgio Conti, Marco Piastra
Sep 21, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Steven L SheinAlexandre T Rotta
Oct 20, 2018·Minerva pediatrica·Andrea WolflerElena Zoia
Feb 1, 2019·The Cochrane Database of Systematic Reviews·Kana R Jat, Joseph L Mathew
Sep 15, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·Daniele De Luca
Jul 11, 2020·Journal of Veterinary Emergency and Critical Care·Vincenzo RondelliFrancesco Staffieri
Aug 26, 2020·Journal of Feline Medicine and Surgery·Caterina Di BellaFrancesco Staffieri
Mar 28, 2020·The Journal of International Medical Research·Tao WangTao Yu
Aug 5, 2017·Journal of Paediatrics and Child Health·Elisa FrassoniDaniele De Luca
May 23, 2020·Annals of Internal Medicine·Holger J SchünemannElie A Akl
Feb 12, 2020·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Raquel Manso Ruiz de la CuestaVerónica García González
Apr 16, 2021·PloS One·Shukun HongLujun Qiao
May 27, 2021·Journal of Tropical Pediatrics·Guojing TangQingxia Shi
Sep 10, 2021·Critical Care : the Official Journal of the Critical Care Forum·Andrea CoppadoroGiacomo Bellani