Continuous warm reperfusion during heart transplantation

The Journal of Thoracic and Cardiovascular Surgery
G PradasA Juffé

Abstract

From April 1991 to January 1993, 37 orthotopic heart transplantations were performed at our institution. Conventional preservation technique with cold crystalloid cardioplegia++ and topical hypothermia during storage and implantation was used in the first 15 cases (group A). After January 1992, for the next 22 patients (group B), we administered a first dose of hyperkalemic blood cardioplegia on arrival of the graft and thereafter instituted continuous warm reperfusion by infusion of oxygenated blood with added potassium. The groups were compared retrospectively, and significant differences were observed. In group B, the ischemic time was shortened by 31 minutes, the suture time lasted 12 minutes longer, sinus rhythm recovered spontaneously, the duration of inotropic support was reduced, postoperative arrythmias decreased, length of intensive care and hospital stays were reduced, there was less ischemic damage in the first endomyocardial biopsy sample, and right ventricular pressures a month after operation were lower. Continuous warm reperfusion during implantation of the donor heart is technically feasible and seems to provide enhanced myocardial preservation.

References

Oct 1, 1992·Journal of Cardiothoracic and Vascular Anesthesia·S Wiese, J Askanazi
Dec 1, 1992·Circulation·R Bolli
Mar 1, 1992·The Annals of Thoracic Surgery·P NatafI Gandjbakhch
Apr 1, 1992·Journal of Cardiothoracic and Vascular Anesthesia·W A Lell
Jan 1, 1991·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·G SootsJ P Devulder
Feb 1, 1991·The Annals of Thoracic Surgery·T A SalernoS V Lichtenstein
Jan 1, 1989·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·C CabrolJ P Levasseur
Dec 1, 1983·European Heart Journal·A FleckensteinG Fleckenstein-Grün

❮ Previous
Next ❯

Citations

Jun 28, 2003·The Journal of Thoracic and Cardiovascular Surgery·Juergen MartinFriedhelm Beyersdorf
Jan 1, 1998·Transplantation Proceedings·G B LucianiA Mazzucco
Feb 21, 2002·Critical Care Nursing Quarterly·L D Nemec, M R DiLucente
Feb 28, 2001·Journal of Cardiac Surgery·J V Conte, W A Baumgartner
Jul 8, 2010·The Journal of Thoracic and Cardiovascular Surgery·Donna M Rudd, Geoffrey P Dobson
Jun 18, 2003·Journal of Cardiac Surgery·Alberto JuffeMarisa Crespo
Jun 25, 2021·World Journal of Transplantation·Jagmeet SinghSandesh Parajuli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
G SootsJ P Devulder
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
M KarckG Uretzky
© 2021 Meta ULC. All rights reserved