Contra-lateral bone loss at the distal radius in postmenopausal women after a distal radius fracture: A two-year follow-up HRpQCT study

Bone
Joost J de JongJoop P W van den Bergh

Abstract

Opposite to the fracture side, bone mineral density (BMD) measured by DXA at the contra-lateral side does not change after a distal radius fracture. However, it is unknown if also bone micro-architecture and strength at the contralateral side are unaffected. Therefore, the aim of this study was to assess BMD, micro-architecture and bone mechanical properties at the contra-lateral side during two years follow-up after a distal radius fracture using high resolution peripheral quantitative computed tomography (HRpQCT). The contra-lateral distal radius of 15 postmenopausal women (mean age 64±8years) with a distal radius fracture treated by cast immobilization was scanned by HRpQCT at baseline, 3months and 2years post-fracture. BMD and cortical and trabecular micro-architecture were measured and biomechanical parameters were estimated using micro finite element analysis (μFEA). Additionally, markers of bone resorption and formation were measured at each visit. Bone parameters and turnover markers across the three visits were analysed using a linear mixed-effect model with Bonferroni correction. Two years post-fracture, a significant decrease from baseline was found in cortical BMD (-4.2%, p<0.001), failure load (-6.1%, p=0.001), sti...Continue Reading

References

Dec 11, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B M IngleR Eastell
Feb 9, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K M FoxR Michael
Apr 6, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·E van der Poest ClementP Lips
Dec 10, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·E van der Poest ClementP Lips
Nov 13, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·B Lawrence RiggsSundeep Khosla
Sep 29, 2005·The Journal of Clinical Endocrinology and Metabolism·Stephanie BoutroyPierre D Delmas
Dec 20, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S W VeitchB M Ingle
Apr 8, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J MagazinerM C Hochberg
Aug 24, 2006·Age and Ageing·Peter Augat, Sandra Schorlemmer
Jan 20, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·N DalzellJ Reeve
Jul 3, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L ReiderUNKNOWN Study of Osteoporotic Fractures Research Group
Mar 12, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Ego SeemanJose Zanchetta
Jun 22, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Andrew J BurghardtSharmila Majumdar
Sep 13, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R RizzoliD Felsenberg
Mar 20, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Angela M CheungAnne E de Papp
May 2, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C E KawalilakS A Kontulainen
Jul 22, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Joy N TsaiBenjamin Z Leder
Mar 31, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C KlopF de Vries
Apr 4, 2015·Journal of Injury & Violence Research·Hosein KarimAlireza Ahmadi
May 24, 2015·Current Opinion in Rheumatology·Yohann BalaEgo Seeman
Aug 9, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C E KawalilakS A Kontulainen
Mar 5, 2016·The Journal of Bone and Joint Surgery. American Volume·Joost J A de JongBert van Rietbergen
Jan 1, 2001·Calcified Tissue International·N J WachterL Claes

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Citations

Jul 6, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J LiuW Xia
Oct 21, 2020·The Journal of Bone and Joint Surgery. American Volume·A M DanielsH M J Janzing

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