Contractile patterns in patients with severe chronic dyspepsia

The American Journal of Gastroenterology
E Björnsson, H Abrahamsson

Abstract

Antroduodenojejunal interdigestive and postprandial pressure recordings were analyzed in 41 consecutive patients referred for evaluation of severe chronic dyspepsia. In addition to traditional manometric evaluation we also focused on the propagation pattern of individual pressure waves in the proximal duodenum. Catheters with closely spaced side holes for temporospatial analysis of the computerized recordings were used. The dominating symptoms were unexplained nausea and vomiting (n = 18), chronic abdominal pain (n = 16), or both (n = 7). The patients' mean age was 45 yr (31 women and 10 men). Gastric surgery had been performed on 11 patients. Results from 20 healthy volunteers served as a reference range. Findings were suggestive of neuropathy in 16 (39%) and myopathy in 1 (2.4%) using conventional criteria. Another 19 patients of the 24 with normal condensed recordings showed abnormalities in the propagation pattern of individual pressure waves in phase II and/or during the fed state, when compared with the controls. Absence of phase III of the migrating motor complex was found in 12 patients during the 5-h fasting recording, compared with none in the controls (p < 0.01). Retroperistalsis at the end of phase III in the duoden...Continue Reading

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Citations

Apr 28, 2005·Chemotherapy·Einar Husebye
Jan 25, 2007·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A ElfvinH Lönroth
Aug 22, 2006·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·S AnderssonH Abrahamsson
Mar 24, 2015·Scandinavian Journal of Gastroenterology·Hans TörnblomHasse Abrahamsson
Aug 25, 2004·Best Practice & Research. Clinical Gastroenterology·Kwang-Jae LeeJan Tack
Jul 11, 2001·Scandinavian Journal of Gastroenterology·H StridE S Björnsson
May 3, 2018·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·D AngJ Tack
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Oct 7, 2006·Current Opinion in Gastroenterology·E M Quigley
Apr 24, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·H Törnblom, H Abrahamsson
Dec 3, 2010·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·F AhlforsH Abrahamsson
Apr 11, 2003·American Journal of Physiology. Gastrointestinal and Liver Physiology·Magnus SimrénJan Tack
Nov 18, 2003·Alimentary Pharmacology & Therapeutics·N S ColemanR C Spiller
Jul 20, 2010·Journal of Pediatric Gastroenterology and Nutrition·G GuarisoP Facchin

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