Contractile properties of human thenar muscles paralyzed by spinal cord injury

Muscle & Nerve
Christine K Thomas

Abstract

The electrical and mechanical properties of paralyzed human thenar muscles were measured in response to supramaximal stimulation of the median nerve in individuals with chronic cervical spinal cord injury. These data were compared to those recorded from control muscles. Spontaneous motor unit activity was common in paralyzed muscles. There was significantly more variance in the twitch and tetanic forces, twitch/tetanus force ratios, twitch and tetanic half-relaxation times, and the stimulus frequencies which generated half-maximal force in paralyzed versus control muscles. Approximately half the paralyzed thenar muscles were significantly weaker than control muscles and their compound action potential amplitudes were reduced significantly. Paralyzed muscles had significantly higher twitch/tetanus force ratios. The mean stimulus frequency which generated half-maximal force was also reduced significantly. Thus for rehabilitation purposes, lower stimulation rates are required to elicit any given submaximal force from chronically paralyzed thenar muscles.

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Citations

Apr 16, 2010·Journal of Neurophysiology·Jason J KutchWilliam Z Rymer
Sep 21, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sudarshan DayanidhiFrancisco J Valero-Cuevas
Feb 9, 2012·The Journal of Physiology·Inge Zijdewind, Christine K Thomas
Jun 19, 2013·Journal of Neuropathology and Experimental Neurology·Yang LiuChristine K Thomas
Jun 19, 2009·Journal of Neuropathology and Experimental Neurology·Robert M GrumblesChristine K Thomas
Aug 26, 2009·Muscle & Nerve·Bo Biering-SørensenFin Biering-Sørensen
Jul 19, 2005·Muscle & Nerve·Christine K Thomas, Inge Zijdewind
Oct 27, 2010·Muscle & Nerve·Gizelda T B CasellaChristine K Thomas
Apr 12, 2012·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Xiaoyan LiPing Zhou
May 24, 2006·Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique·M BaratM de Seze
Jun 29, 2016·Journal of Neurotrauma·Robert M Grumbles, Christine K Thomas
Jan 11, 2001·Muscle & Nerve·R M Enoka, A J Fuglevand
Jul 13, 2002·Muscle & Nerve·Sharlene GodfreyChristine K Thomas
Sep 10, 2011·Neurorehabilitation and Neural Repair·Inge ZijdewindChristine K Thomas
May 18, 2018·Journal of Applied Physiology·Bradley A DeForestChristine K Thomas
Nov 12, 2005·Journal of Neurophysiology·R Luke W HarrisDavid J Bennett
Apr 14, 2006·Journal of Neurophysiology·C K Häger-RossC K Thomas
Mar 4, 2006·The Journal of Physiology·C S KleinC K Thomas
Dec 13, 2006·Journal of Applied Physiology·Krzysztof E KowalskiAnthony F DiMarco
Aug 2, 2013·Acta Physiologica·C K ThomasI Zijdewind
Mar 4, 2003·Journal of Neurophysiology·Christine K ThomasJane E Butler
Sep 26, 2019·Artificial Organs·Luciane Patrícia Adreani CabralEduardo M Scheeren
Aug 22, 2000·Muscle & Nerve·B Bigland-RitchieC K Thomas
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·M EstenneA De Troyer
Oct 23, 2002·Journal of Applied Physiology·Jane E Butler, Christine K Thomas
Apr 27, 2002·Journal of Neurophysiology·Lisa GriffinChristine K Thomas
May 21, 2021·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Xiaoyan LiPing Zhou

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