journal cover

Contractile properties of various histaprodifen derivatives in guinea pig isolated ileum and trachea

Pharmacology

Dec 14, 2006

B ChristopheRoy Massingham

Abstract

We characterized the histamine H(1) receptor agonism of various histaprodifen derivatives in guinea pig isolated ileum and trachea in comparison with histamine. Based on their affinity (calculated pK(A) values for ileum and trachea, respectively), the compounds were ranked as follows: s...read more

Mentioned in this Paper

Histamine
Ceplene
Histamine Measurement
Ileum
Zetir
Derivatives
Agonists
Muscle Contraction
Antihistamines, Classical
Allergy Testing Histamine (Lab Test)
Paper Details
References
  • References23
  • Citations24
123
  • References23
  • Citations24
123

Contractile properties of various histaprodifen derivatives in guinea pig isolated ileum and trachea

Pharmacology

Dec 14, 2006

B ChristopheRoy Massingham

PMID: 17164592

DOI: 10.1159/000097929

Abstract

We characterized the histamine H(1) receptor agonism of various histaprodifen derivatives in guinea pig isolated ileum and trachea in comparison with histamine. Based on their affinity (calculated pK(A) values for ileum and trachea, respectively), the compounds were ranked as follows: s...read more

Mentioned in this Paper

Histamine
Ceplene
Histamine Measurement
Ileum
Zetir
Derivatives
Agonists
Muscle Contraction
Antihistamines, Classical
Allergy Testing Histamine (Lab Test)

Related Papers

Paper Details
References
  • References23
  • Citations24
123
  • References23
  • Citations24
123
/papers/contractile-properties-of-various-histaprodifen/17164592