Contractility of seminiferous tubules as related to sperm transport in the male

Archives of Andrology
L C EllisR J Tesi

Abstract

The mammalian testes have several mechanisms to propel the nonmotile spermatozoa in the seminiferous tubules through the rete testis into the epididymis. These include (a) contractions of the testicular capsule and the seminiferous tubules and (b) fluid flow through the excurrent ducts resulting from active transport of fluids and electrolyte into the seminiferous tubules from the extracellular space. The efflux of fluids and sperm from the testis appears to closely parallel spermiation. An increased output of fluid may result from prostaglandins (PGF2 alpha) and possibly oxytocin (not all species respond to oxytocin) as a result of capsular contractions compressing and expelling the fluid from the tubules. Seminiferous tubular contractions do not result from nervous stimulation but are linked to PGs and cyclic nucleotide generation. They are regulated to some extent by androgens and the lesser response of the tubules to 5 alpha-dihydrotestosterone compared to testosterone can be explained by their interaction with androgen binding protein and their action on phospholipase A2 activity for PG synthesis.

References

Jun 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·S H OngA L Steiner
Sep 1, 1977·Journal of Reproduction and Fertility·J M Johnson, L C Ellis
Sep 1, 1979·Journal of Reproduction and Fertility·C OhanianR A Roca
Mar 1, 1979·Journal of Animal Science·T E PilbeamH F Travis
Apr 1, 1975·The Journal of Urology·C F FirlitJ R Davis
Apr 1, 1975·Journal of Reproduction and Fertility·J K Voglmayr
Jan 1, 1975·The Tohoku Journal of Experimental Medicine·M ShiraiS Matsuda
Nov 19, 1975·Cell and Tissue Research·K Unsicker, G Burnstock
Feb 1, 1973·Journal of Reproduction and Fertility·C Bell, J R McLean
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·O Hovatta
Dec 30, 1971·Annals of the New York Academy of Sciences·L TrinerS H Ngai
Jan 1, 1972·Zeitschrift Für Anatomie Und Entwicklungsgeschichte·M Kormano, O Hovatta
Nov 1, 1972·The Tohoku Journal of Experimental Medicine·A Rikimaru, T Suzuki
Nov 1, 1972·The Tohoku Journal of Experimental Medicine·A RikimaruI Dendo
Jan 1, 1973·Proceedings of the Society for Experimental Biology and Medicine·J L HargroveL C Ellis
Mar 1, 1974·Proceedings of the Society for Experimental Biology and Medicine·H D HafsJ N Stellflug
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·O Hovatta
Mar 1, 1971·Proceedings of the Society for Experimental Biology and Medicine·J L HargroveL C Ellis
Aug 1, 1969·Journal of Reproduction and Fertility·J R Davis, G A Langford
Oct 1, 1965·Journal of Reproduction and Fertility·N Hodson
Sep 1, 1962·The Anatomical Record·T S LEESON
Oct 1, 1974·Journal of Morphology·Thomas S Leeson, Frank B Cookson

❮ Previous
Next ❯

Citations

Feb 24, 2001·Toxicologic Pathology·G L Foley
Nov 11, 2005·Biology of Reproduction·Frederick C L BanksGeoffrey Burnstock
Mar 16, 2006·The Journal of Toxicological Sciences·Tze-Kiong ErJau-Nan Lee
May 14, 2005·Annals of the New York Academy of Sciences·Gilda CobellisSilvia Fasano
Sep 27, 2003·International Journal of Andrology·Silvina B MeroniSelva B Cigorraga
Nov 27, 2018·Reproduction in Domestic Animals = Zuchthygiene·Cholayuth BhanmeechaoSuppawiwat Ponglowhapan
Mar 1, 1997·Journal of Cellular Biochemistry·J ChenJ A Tischfield
Jun 15, 2011·Physiology·Ye Chun RuanHsiao Chang Chan
Jan 1, 1988·Journal of Andrology·M NistalR Paniagua
Apr 24, 2020·Andrologia·Manish KuchakullaRanjith Ramasamy
Nov 17, 2020·Frontiers in Endocrinology·Beatrix StadlerRalf Middendorff
Sep 13, 1989·European Journal of Pharmacology·M SánchezF Andres-Trelles
Jul 16, 2021·Theriogenology·Daniel Andrews de Moura FernandesFelipe Zandonadi Brandão

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.