Contrast-enhanced intraoperative ultrasonography in surgery for liver tumors

European Journal of Radiology
G Torzilli

Abstract

IOUS is the most accurate diagnostic technique for assessing focal liver lesions, but still has some drawbacks. Contrast-enhanced ultrasound examination done intraoperatively (CE-IOUS), using second generation contrast agents (SonoVue, Bracco-Imaging, Milan, Italy), seems able to overcome those aforementioned lacking aspects of IOUS. In cirrhotic patients with hepatocellular carcinoma (HCC), CE-IOUS provides information about tumor vascularity which are useful for nodules differentiation: this should improve the surgical radicality. Furthermore, two different pattern of enhancement are also recognizable at CE-IOUS in those HCC nodules depicted preoperatively: one of them has no similarity with that observed at computed tomography (CT). In patients who undergo surgery for colorectal liver metastases, CE-IOUS seems to improve the sensitivity of IOUS to small, hypoechoic lesions, reducing the risk to down-stage the disease and enhancing the rate of treatment with curative intent. In conclusion, IOUS accuracy is improved by CE-IOUS with an impact on surgical strategy either for primary than for metastatic tumors. Furthermore, a wider experience with vascular enhancement patterns at CE-IOUS could provide new classification for liver...Continue Reading

References

May 1, 1989·Annals of Surgery·G A ParkerM J Koretz
Sep 1, 1986·The British Journal of Surgery·I G Finlay, C S McArdle
Oct 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M RoncalliM Borzio
Apr 24, 2001·Ultrasound in Medicine & Biology·Y TakigawaM Makuuchi
Sep 28, 2004·The British Journal of Surgery·G TorzilliM Makuuchi

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Citations

Feb 12, 2009·Medical & Biological Engineering & Computing·David Cosgrove, Chris Harvey
Dec 20, 2005·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Wolfgang SchimaAhmed Ba-Ssalamah
Feb 22, 2008·AJR. American Journal of Roentgenology·Linda ChamiDominique Elias
Jan 11, 2011·World Journal of Gastroenterology : WJG·Michiel Postema, Odd Helge Gilja
Jul 22, 2006·Abdominal Imaging·M D'OnofrioR Pozzi Mucelli
Dec 1, 2009·Journal of Ultrasound·M D'OnofrioR Pozzi Mucelli
Nov 1, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Gianluca MazzoniAdriano Tocchi
Aug 20, 2016·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Rahul SastryAlexandra J Golby
Mar 9, 2021·The British Journal of Radiology·Meghan G LubnerPerry Pickhardt

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