Contrast-enhanced ultrasonography in differential diagnosis of benign and malignant ovarian tumors

PloS One
Jing-Jing QiaoMan Li

Abstract

To evaluate the accuracy of contrast-enhanced ultrasonography (CEUS) in differential diagnosis of benign and malignant ovarian tumors. The scientific literature databases PubMed, Cochrane Library and CNKI were comprehensively searched for studies relevant to the use of CEUS technique for differential diagnosis of benign and malignant ovarian cancer. Pooled summary statistics for specificity (Spe), sensitivity (Sen), positive and negative likelihood ratios (LR+/LR-), and diagnostic odds ratio (DOR) and their 95%CIs were calculated. Software for statistical analysis included STATA version 12.0 (Stata Corp, College Station, TX, USA) and Meta-Disc version 1.4 (Universidad Complutense, Madrid, Spain). Following a stringent selection process, seven high quality clinical trials were found suitable for inclusion in the present meta-analysis. The 7 studies contained a combined total of 375 ovarian cancer patients (198 malignant and 177 benign). Statistical analysis revealed that CEUS was associated with the following performance measures in differential diagnosis of ovarian tumors: pooled Sen was 0.96 (95%CI = 0.92∼0.98); the summary Spe was 0.91 (95%CI = 0.86∼0.94); the pooled LR+ was 10.63 (95%CI = 6.59∼17.17); the pooled LR- was 0.04...Continue Reading

References

Jun 15, 2004·Health Technology Assessment : HTA·P WhitingJ Kleijnen
Jun 16, 2005·Bioinformatics·Elias Zintzaras, John P A Ioannidis
Feb 10, 2006·JAMA : the Journal of the American Medical Association·Jaime L PetersLesley Rushton
Mar 8, 2006·BMC Medical Research Methodology·Penny F WhitingJos Kleijnen
Dec 13, 2006·Radiologic Clinics of North America·Svetlana MironovLucy E Hann
Dec 29, 2006·Contrast Media & Molecular Imaging·A L KlibanovS Kaul
Jan 9, 2007·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·L BolondiF Piscaglia
Jun 26, 2008·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Arthur C FleischerDavid A Fishman
Jun 11, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hao-Sha TangLiang-Qing Yao
Jun 23, 2009·AJR. American Journal of Roentgenology·Stephanie R WilsonBarry B Goldberg
Jul 4, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Malgorzata BanysTanja Fehm
Sep 26, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Arthur C FleischerDavid A Fishman
Nov 12, 2009·BMC Medical Research Methodology·Taye H HamzaTheo Stijnen
Feb 11, 2010·Journal of Clinical Ultrasound : JCU·P G SorelliA K P Lim
Apr 9, 2010·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Wu XingLi Ao
Apr 24, 2010·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S R Rafaelsen, A Jakobsen
Oct 12, 2010·European Radiology·Emilio Quaia
Jan 13, 2011·Recent Patents on Cardiovascular Drug Discovery·Shiva Dindyal, Constantinos Kyriakides
Aug 19, 2011·World Journal of Urology·Martijn SmeengeHessel Wijkstra
Aug 15, 2012·American Journal of Primatology·J M HastingsC M Moran

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Citations

Aug 8, 2019·Revista da Associação Médica Brasileira·Xiali WangWeina Zhang
Apr 14, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Changtian LiJunlai Li
Apr 2, 2019·Contrast Media & Molecular Imaging·Xuejin OuXuelei Ma
May 1, 2021·Animals : an Open Access Journal From MDPI·Marco RussoGabriele Marino

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Methods Mentioned

BETA
imaging technique

Software Mentioned

Disc
STATA
QUADAS
Meta

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