CONTRAST-ENHANCED ULTRASONOGRAPHY OF THE PANCREAS IN HEALTHY DOGS AND IN DOGS WITH ACUTE PANCREATITIS

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Nathalie RademacherLorrie Gaschen

Abstract

Pancreatitis is the most frequent disease affecting the exocrine pancreas in dogs and reliable diagnostic techniques for predicting fatal complications are lacking. Contrast-enhanced ultrasound (CEUS) improves detection of tissue perfusion as well as organ lesion vascular pattern. Objectives of this prospective case control study were to compare perfusion characteristics and enhancement patterns of the pancreas in healthy dogs and dogs with pancreatitis using CEUS. Ten healthy dogs and eight dogs with pancreatitis were selected based on physical examination, abdominal ultrasound, and blood analysis findings. A CEUS study of the pancreas was performed for each dog and two observers who were aware of clinical status used advanced ultrasound quantification software to analyze time-intensity curves. Perfusion patterns were compared between healthy and affected dogs. In dogs with acute pancreatitis, mean pixel and peak intensity of the pancreatic parenchyma was significantly higher than that of normal dogs (P = 0.05) in between 6 and 60 s (P = <0.0001-0.046). This corresponds to a 311% increase in mean pixel intensity in dogs with acute pancreatitis compared to healthy dogs. Wash-in rates were greater and had a consistently steeper ...Continue Reading

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Citations

Feb 8, 2016·The Veterinary Clinics of North America. Small Animal Practice·Martha Moon Larson
Nov 27, 2018·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Thorsten RickKatharina M Hittmair
Jan 28, 2020·American Journal of Veterinary Research·Timothy B KloerAngela J Marolf
Oct 5, 2019·The Veterinary Record·Tommaso BanzatoAlessandro Zotti
Aug 23, 2020·Animals : an Open Access Journal From MDPI·Francesco SimeoniMassimo Vignoli
Apr 4, 2021·Animals : an Open Access Journal From MDPI·Francesco SimeoniMassimo Vignoli
Nov 10, 2021·Journal of Veterinary Internal Medicine·Harry CridgeJörg M Steiner

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