Contrast-enhanced ultrasound -guided axillary lymph node core biopsy: Diagnostic accuracy in preoperative staging of invasive breast cancer

European Journal of Radiology
Suvi RautiainenAnna Sutela

Abstract

To evaluate accuracy of contrast enhanced ultrasound (CEUS)-sentinel procedure followed by core biopsy (CB) and marking in patients with breast cancer. To compare the axillary metastatic tumour burden in patients with positive vs. negative CB results. Two radiologists in our tertiary care hospital performed axillary CEUS sentinel procedures on consecutive US node negative breast cancer patients. The first enhancing lymph node (LN) was core biopsied and marked with a breast coil. The results were compared to final histopathology. We analysed the diagnostic performance of CEUS CB and its ability to detect patients with higher axillary burden (>2 metastasis). During the study period between January 2013 and December 2014, altogether 54 patients (mean age 60.4 years) were included in the statistical analysis. The sensitivity for CEUS CB was 66.7%, specificity 100%, PPV 100%, NPV 93.8% and overall accuracy 94.4%. The method correctly recognised all the axillae with higher tumour burdens (sensitivity 100%, N=3) and 59.3% of coils marking the LNs were discovered. CEUS -guided axillary CB proved to be feasible and accurate procedure with moderate sensitivity and it clearly identified the higher axillary tumour burden. The coil marking ...Continue Reading

References

Apr 25, 2006·AJR. American Journal of Roentgenology·Soledad AlvarezJulia Cortés
Nov 11, 2008·The Breast : Official Journal of the European Society of Mastology·P D BrittonG C Wishart
Aug 23, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S E HarnanL Wyld
May 2, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K CoxP Jones
May 6, 2014·Radiologic Clinics of North America·Cecilia L Mercado
Mar 11, 2015·Journal of Surgical Oncology·Chantal ReynaMarie Catherine Lee

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Citations

May 15, 2016·Ultrasonics·John R EisenbreyFlemming Forsberg
Jan 4, 2017·Dento Maxillo Facial Radiology·Shalva R GvetadzeJian Sun
Jun 2, 2018·Journal of Immunology Research·Wei LvLi Zhang

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