Contrast enhanced ultrasound (CEUS) to assess pleural pulmonal changes in severe COVID-19 infection: First results

Clinical Hemorheology and Microcirculation
E M JungF Jung

Abstract

Use of contrast enhanced ultrasound (CEUS) in severe cases of COVID-19 infection to assess pulmonary changes near the pleura. Bedside examinations by an experienced intensive care unit examiner using a multi-frequency probe (C1-6 MHz) with B-mode and CEUS to assess pleural-near changes in severe cases of COVID-19 infection with respiratory failure. CEUS with bolus delivery via a central venous catheter of 2.4 ml Sulphur hexafluoride microbubbles from the arterial phase (10-15 s) to the late phase of 5 min. Digital storage of cine sequences of the lung sound with abdomen for independent assessment with the subsequently performed contrast-enhanced dual-source CT. In 11 intubated and ventilated patients (arithmetic mean 62 years, 48 to 78 years, 3 women) with confirmed severe COVID-19 infections, a peripherally accentuated consolidation with irregular hyperemia was found in the CEUS and also in the CT examination. Of the 5 cases with pulmonary arterial embolisms, signs of right ventricular failure were found. In all cases, using CEUS low perfused areas of the pleura with adjacent hyperemia could be detected, while, with CT segmental contrast medium, gaps with subpleural compressions were found. Interstitial changes near the pleura...Continue Reading

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Citations

Sep 1, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Gino SoldatiLibertario Demi
Oct 20, 2020·Clinical Hemorheology and Microcirculation·Johanes NugrohoImanita Septianda
Jan 19, 2021·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ehsan Safai ZadehCorinna Trenker
Mar 9, 2021·Science China. Chemistry·Chen ZhangZhe Liu
May 4, 2021·Clinical Hemorheology and Microcirculation·Ying-Hua SunChao Chen
Dec 17, 2020·Archivos de bronconeumología·Ivan VollmerMarcelo Sánchez
Jun 6, 2021·Archivos de bronconeumología·Ivan VollmerMarcelo Sánchez
Sep 14, 2021·Clinical Hemorheology and Microcirculation·Cesare TripolinoMauro Silingardi

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