Contrast-enhanced ultrasound examination of lymph nodes in different types of lymphoma

Cancer Detection and Prevention
Kazunori NakaseHiroshi Shiku

Abstract

Since the tumor growth depends on the formation of feeding vessels, color/power Doppler ultrasonography (US) has been used to evaluate the vascular flow images of lymph nodes (LNs) in order to differentiate benign LNs from malignant LNs or lymphoma from metastatic carcinoma. We performed color/power Doppler ultrasonography (US) using Levovist (LV) to evaluate the vascular patterns in the LNs of 10 patients with different types of lymphoma. The patterns were classified as central, peripheral, or avascular type. Vascular flow was identified in 9 of 10 LNs and it was enhanced with LV in all cases. The vascular pattern of the LNs was of the central type in all seven B-cell lymphoma patients and one of two T-cell lymphoma patients and of the peripheral type in the remaining T-cell lymphoma patient. The avascular type pattern was observed in one Hodgkin lymphoma patient even with LV. Typical vascular patterns might be associated with certain subtypes of lymphoma, and LV appears to improve the diagnostic value of Doppler US.

References

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Citations

Sep 25, 2007·Journal of Cancer Research and Clinical Oncology·Michael HockeAndreas Stallmach
Jan 11, 2011·World Journal of Gastroenterology : WJG·Nischita K ReddyManoop S Bhutani
Aug 16, 2013·World Journal of Gastroenterology : WJG·Xin-Wu CuiChristoph F Dietrich
Apr 5, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Joo Kyung SimHyun Sook Hong

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