Contrast-Enhanced Ultrasound in Small Intestinal Ischemia: Proof of Concept.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Sriharsha GummadiJohn R Eisenbrey

Abstract

Small intestinal ischemia is a challenging diagnosis to make, even with the combination of imaging, laboratory analysis, and physical exam. This pilot study investigated the role of CEUS in evaluating small bowel wall vascularity in participants with suspected ischemia. In this IRB-approved pilot study, CEUS using perflutren lipid microspheres (DEFINITY®; Lantheus Medical Imaging Inc., N. Billerica, MA) was performed on participants determined by the clinical surgical team to have concerns for small intestinal ischemia. CEUS interpretations were performed at both the bedside and later by a blinded radiologist and compared to clinical imaging, surgical findings, or long-term clinical outcomes. Fifteen CEUS examinations were performed on 14 participants. Five of the participants underwent exploratory laparotomy. Of these, one had small intestinal ischemia (without necrosis). Point of care CEUS demonstrated no evidence of bowel necrosis in any case, and delayed enhancement (indicative of intestinal ischemia) in three cases, resulting in a sensitivity of 100% (95% CI 2.5-100%) and specificity of 85.7% (95% CI 57.2-98.2%). CEUS correctly ruled out ischemia in 91.7% of cases with CT suspicion of small bowel obstruction and 60% of cas...Continue Reading

References

May 8, 1999·The European Journal of Surgery = Acta Chirurgica·N MamodeP Leiberman
Mar 28, 2003·Radiologic Clinics of North America·Ah Young Kim, Hyun Kwon Ha
Jul 26, 2005·Radiology·Jiro HataHiroaki Kusunoki
Jul 6, 2010·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Barbara BradenChristoph Dietrich
Feb 25, 2011·The New England Journal of Medicine·Christopher L Moore, Joshua A Copel
Aug 30, 2011·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·F PiscagliaH P Weskott
Dec 27, 2012·The Journal of Trauma and Acute Care Surgery·Adrian A MaungUNKNOWN Eastern Association for the Surgery of Trauma
Jan 9, 2013·Abdominal Imaging·Isabel B OlivaKarin E Dill
Jun 14, 2013·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Mark R Taylor, Nadim Lalani
Nov 19, 2013·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Michael T CudnikBrian C Hiestand
Sep 25, 2015·The Journal of Trauma and Acute Care Surgery·Dan AzaguryDavid A Spain
Dec 21, 2017·Abdominal Radiology·Alexandra MedellinStephanie R Wilson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Swiss Medical Weekly
F J ten Cate
Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Yan ZhouXiang Jing
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
C BeatonN Kumar
© 2021 Meta ULC. All rights reserved