PMID: 16538196Mar 16, 2006Paper

Contrast-enhanced, wide-band, phase inversion harmonic power Doppler imaging of hepatocellular carcinoma

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Jacek JanicaSławomir Dobrzycki

Abstract

Early diagnosis of hepatocellular carcinoma (HCC) is extremely important because surgical resection and local ablation therapy are undoubtfully the most effective treatment regiment. Recent advances in sonographic techniques have risen the question ofsonography utility. The scope of this investigation was to assess the detection accuracy of tumor vascularity in HCC by contrast-enhanced, wide-band phase inversion (PI) power Doppler sonography. Twenty-one patients were examined with 21 nodules (16 hypo-, 2 iso-, 3 hyperechoic nodules). The presence of hepatocellular carcinoma was confirmed by fine-needle biopsy results in 16 nodules, and the diagnosis in the remaining tumors was based on imaging findings and tumor markers. All patients, prior to enhanced sonography, had undergone both the native B-mode and tissue harmonic imaging mode sonography, color Doppler, and power Doppler examinations. Three patients were excluded. 18 nodules evaluation by contrast-enhanced, wide-band PI power Doppler US revealed tumor vessels in 100% cases in arterial phase. The characteristic chaotic pattern of lesions vascularity was evidently pronounced. Rapid increase of enhancement during the arterial and slow decrease of enhancement during the porta...Continue Reading

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