Contrast-induced nephropathy (CIN) of patients with renal dysfunction in CT examination

Japanese Journal of Radiology
Yasuhiro FukushimaYoshito Tsushima

Abstract

To investigate the incidence and risk factors of contrast induced nephropathy (CIN) after contrast enhanced (CE) computed tomography (CT) in patients with renal dysfunction. Two hundred sixteen inpatients with estimated glomerular filtration rates (eGFR) <60 ml/min/1.73 m2 underwent CE CT using iodine doses of 420 or 480 mg I/kg. Data of all enrolled patients was collected for baseline serum creatinine level (SCr), post-CE CT SCr within 3 days after CE CT, and conditions considered risk factors for CIN [renal dysfunction, contrast media dose, advanced age, diabetes mellitus, no intravenous hydration, cardiac dysfunction (left ventricular ejection fraction <60%) and intensive-care unit (ICU) admission]. CIN was defined as an increase in SCr level of more than 0.5 mg/dl or more than 25% from baseline within 3 days post-CE CT without any other identifiable cause of acute kidney injury. The incidence of CIN was 11/216 (5.1%) and was associated with cardiac dysfunction [odds ratio (OR) 6.540; 95% confidence interval (CI) 1.090-39.300; p = 0.040] and ICU admission (OR 11.500; 95% CI 2.050-64.100; p = 0.005). Our results suggested that cardiac dysfunction and ICU admission may be risk factors for CIN in patients with preexisting renal...Continue Reading

References

Apr 30, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Kevin NashSusan Hou
Sep 5, 2006·The American Journal of Cardiology·Norbert LameireUNKNOWN CIN Consensus Working Panel
May 9, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Steven D WeisbordMichael J Fine
Dec 8, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Alice M MitchellJeffrey A Kline
Jan 26, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sun Moon KimYon Su Kim
May 21, 2010·Artificial Organs·Gaetano La MannaSergio Stefoni
Jul 31, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Marcus CarlssonHakan Arheden

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Citations

Nov 12, 2019·Japanese Journal of Radiology·Yoshitaka IsakaUNKNOWN Japanese Society of Nephrology, Japan Radiological Society, and Japanese Circulation Society Joint Working Group
Nov 12, 2019·Clinical and Experimental Nephrology·Yoshitaka IsakaUNKNOWN Japanese Society of Nephrology, Japan Radiological Society, and Japanese Circulation Society Joint Working Group
Nov 12, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshitaka IsakaUNKNOWN Japanese Circulation Society Joint Working Group
May 23, 2020·Radiología·A Barrios LópezC Martín-Hervás
Jul 12, 2021·Radiología·A Barrios LópezC Martín-Hervás

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