Contrast opacification using a reduced volume of iodinated contrast material and low peak kilovoltage in pulmonary CT angiography: Objective and subjective evaluation

AJR. American Journal of Roentgenology
Andetta R HunsakerFrank J Rybicki

Abstract

The purpose of our study was to evaluate whether a reduced volume of iodinated contrast material for pulmonary CT angiography (CTA) using a low peak kilovoltage (kVp) technique yields equivalent opacification in all vessels. Four hundred fifty-two consecutive pulmonary CTA patients (265 women and 187 men; age range, 18-91 years; mean age, 56.2 years) were retrospectively evaluated. Patients were grouped into those receiving 125 mL (n = 229) and 75 mL (n = 223) of 370 mg I/mL iodinated contrast material. Low kVp was used in all patients. Hounsfield units were measured at lobar, posterobasal segment, posterobasal ramus, and medial basal subsegmental ramus in the left lower lobe. Three thoracic radiologists blinded to contrast dose independently and randomly evaluated the quality of enhancement using a 3-point scale at the same levels. The two-sample Student's t test was used to compare contrast opacification between groups; Spearman's correlation and the C-statistic were used to assess objective and subjective measurements. Interreader agreement was measured using Kendall's coefficient. Mean contrast opacification differences between 125 mL versus 75 mL were not statistically significant (p > 0.21) at the lobar, segmental, and po...Continue Reading

References

Nov 1, 1995·AJR. American Journal of Roentgenology·M Remy-JardinJ P Beregi
Jan 30, 2002·Radiologic Clinics of North America·Kavita Garg
Apr 28, 2005·JAMA : the Journal of the American Medical Association·Rene QuirozU Joseph Schoepf
Jan 24, 2007·AJR. American Journal of Roentgenology·Chang Hyun LeeK T Bae
Feb 22, 2008·AJR. American Journal of Roentgenology·Kyongtae T BaePamela K Woodard
Jul 19, 2008·European Radiology·Kyongtae Ty Bae, Jay P Heiken

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Citations

Feb 24, 2011·AJR. American Journal of Roentgenology·Markus WeiningerU Joseph Schoepf
Nov 22, 2014·AJR. American Journal of Roentgenology·Yajuan WangSandra S Halliburton
Aug 2, 2014·The International Journal of Cardiovascular Imaging·Kanako K KumamaruAndetta R Hunsaker
May 25, 2012·AJR. American Journal of Roentgenology·Philip A AraozPatrick M Colletti
May 5, 2017·The British Journal of Radiology·Andrik J AschoffThomas Albrecht
Mar 27, 2012·Journal of Computer Assisted Tomography·Dawn Renae EngelkemierAfshin Karimi
May 22, 2020·The British Journal of Radiology·Hanan AlobeidiMats Lidén

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