Contrasting HCV and HIV seroepidemiology in 11 years of blood donors screening in Brazil

Transfusion Medicine
J E LeviJ M Kutner

Abstract

Blood donors are, in principle, healthy individuals who may be revealed as infectious for blood-borne agents by the laboratory screening process, depicting the asymptomatic burden of the disease. Therefore, monitoring hepatitis C virus (HCV)-infected donor and human immunodeficiency virus (HIV)-infected donor and associating to their demographical and behavioural characteristics may shed light on the dynamics and contemporary changes in these viruses' epidemiology. Donors presenting repeatedly reactive HCV or HIV serology/nucleic acid testing (NAT) screening results were submitted to confirmatory testing. Confirmed positive donors were invited to return to the blood bank for notification and counselling when a follow-up sample was obtained and an interview performed to eventually disclose potential risks. HCV- or HIV-infected donors identified over 11 years of screening (2004-2015) were evaluated for demographic and behavioural parameters. In the period, 139 160 donations were screened, and 36 (0.025%) were found positive for HIV, stemming from 29 male and 7 female donors. Among those, eight subjects were repeat donors. A total of 95 donations were found repeatedly reactive for HCV (0.068%), obtained from 60 men and 35 women. N...Continue Reading

References

Dec 4, 2002·AIDS·Guido Carlos Levi, Marco Antonio A Vitória
Oct 11, 2011·Transfusion·Ester C SabinoUNKNOWN NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component
Jun 22, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R Monina KlevensScott D Holmberg
Aug 14, 2012·Transfusion·Cesar de Almeida-NetoUNKNOWN NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component
Feb 5, 2013·BMC Infectious Diseases·Leila M M B PereiraRicardo A A Ximenes
Oct 23, 2013·Transfusion·Nanci Alves SallesAlfredo Mendrone Júnior
Dec 5, 2014·Transfusion·Brian CusterUNKNOWN NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II)

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Citations

Mar 30, 2018·Frontiers in Medicine·José Eduardo Levi

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