Contrasting mode of evolution at a coat color locus in wild and domestic pigs.

PLoS Genetics
Meiying FangLeif Andersson

Abstract

Despite having only begun approximately 10,000 years ago, the process of domestication has resulted in a degree of phenotypic variation within individual species normally associated with much deeper evolutionary time scales. Though many variable traits found in domestic animals are the result of relatively recent human-mediated selection, uncertainty remains as to whether the modern ubiquity of long-standing variable traits such as coat color results from selection or drift, and whether the underlying alleles were present in the wild ancestor or appeared after domestication began. Here, through an investigation of sequence diversity at the porcine melanocortin receptor 1 (MC1R) locus, we provide evidence that wild and domestic pig (Sus scrofa) haplotypes from China and Europe are the result of strikingly different selection pressures, and that coat color variation is the result of intentional selection for alleles that appeared after the advent of domestication. Asian and European wild boar (evolutionarily distinct subspecies) differed only by synonymous substitutions, demonstrating that camouflage coat color is maintained by purifying selection. In domestic pigs, however, each of nine unique mutations altered the amino acid se...Continue Reading

References

Sep 1, 1995·Mammalian Genome : Official Journal of the International Mammalian Genome Society·H KlunglandS Lien
Aug 1, 1996·Trends in Genetics : TIG·G S Barsh
Dec 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·L MarklundL Andersson
Nov 3, 1998·Genetics·J M KijasL Andersson
Jan 20, 1999·Mammalian Genome : Official Journal of the International Mammalian Genome Society·D I VågeR D Cone
Dec 22, 1999·Mammalian Genome : Official Journal of the International Mammalian Genome Society·J M NewtonG S Barsh
Aug 26, 2000·Molecular Biology and Evolution·J Zhang, M Nei
Jun 29, 2001·Journal of Molecular Evolution·J M Kijas, L Andersson
Aug 27, 2004·Molecular Biology and Evolution·Yun-Huei TzengWen-Hsiung Li
Jan 18, 2006·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Cord DrögemüllerTosso Leeb
Feb 24, 2007·The Plant Journal : for Cell and Molecular Biology·Amanda R WalkerSimon P Robinson
May 10, 2007·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Sep 13, 2007·Proceedings. Biological Sciences·Taehwan LeeDiarmaid O Foighil

❮ Previous
Next ❯

Citations

Aug 15, 2014·PloS One·Izabella Baranowska KörbergLeif Andersson
Oct 2, 2013·TheScientificWorldJournal·Guang-Li YangYu-Zhu Luo
Apr 24, 2014·Proceedings of the National Academy of Sciences of the United States of America·Greger LarsonDorian Q Fuller
Jul 31, 2014·Heredity·S E Ramos-OnsinsM Amills
Dec 3, 2014·Forensic Science International : Synergy·George D ZouganelisGarry Scarlett
Apr 22, 2009·Proceedings of the National Academy of Sciences of the United States of America·T Douglas Price
Jul 23, 2009·BMC Evolutionary Biology·Terhi Iso-TouruJohanna Vilkki
May 27, 2010·Heredity·A OjedaM Pérez-Enciso
Jun 16, 2011·PloS One·Arun KommadathMari A Smits
Sep 3, 2011·Proceedings. Biological Sciences·Pamela Wiener, Samantha Wilkinson
Jan 25, 2013·Journal of Animal Science and Biotechnology·Wanjie YangMeiying Fang
Mar 19, 2013·BMC Genomics·Anna Esteve-CodinaMiguel Pérez-Enciso
Oct 8, 2013·PloS One·Morgane OllivierCatherine Hänni
May 13, 2010·British Poultry Science·A-C KarlssonP Jensen
Dec 15, 2012·Immunogenetics·Katerina A MoutouZissis Mamuris
Oct 27, 2012·Yi chuan = Hereditas·Xiu-Ling LiBin Fan
Apr 25, 2009·Science·Arne LudwigMichael Hofreiter
Feb 19, 2013·Trends in Genetics : TIG·Greger Larson, Joachim Burger
Dec 26, 2012·Veterinary Microbiology·Cristina Cano-GómezMiguel Angel Jiménez-Clavero
Jun 19, 2012·Physiological and Biochemical Zoology : PBZ·Ismael GalvánJuan J Negro
Dec 14, 2011·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Emma M SvenssonAnders Götherström
Apr 13, 2010·Trends in Genetics : TIG·Joanna K HubbardRebecca J Safran
Dec 25, 2015·Proceedings. Biological Sciences·Mirte BosseMartien A M Groenen
Nov 27, 2010·Animal Science Journal = Nihon Chikusan Gakkaihō·Huirong MaoLusheng Huang
Oct 20, 2015·Upsala Journal of Medical Sciences·Leif Andersson
Nov 17, 2009·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·Stefan Rieder
Jun 4, 2010·Animal Genetics·L F GroeneveldUNKNOWN GLOBALDIV Consortium

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

SEQUENCHER
MEGA4

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Greger LarsonAlan Cooper
Mammalian Genome : Official Journal of the International Mammalian Genome Society
M Johansson MollerL Andersson
© 2021 Meta ULC. All rights reserved