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Contrasting the genetic architecture of 30 complex traits from summary association data

bioRxiv

Jan 4, 2016

Huwenbo ShiBogdan Pasaniuc

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Abstract

Variance components methods that estimate the aggregate contribution of large sets of variants to the heritability of complex traits have yielded important insights into the disease architecture of common diseases. Here, we introduce new methods that estimate the total variance in trait...read more

Mentioned in this Paper

BAT Loci
Single Nucleotide Polymorphism
Dysequilibrium Syndrome
Genetic Linkage
Genome
Genome-Wide Association Study
Genetic Loci
EAF2 gene
Local
Locus
28
204
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  • Contrasting the genetic architecture of 30 complex traits from summary association data

    bioRxiv

    Jan 4, 2016

    Huwenbo ShiBogdan Pasaniuc

    PMID: 990035907

    DOI: 10.1101/035907

    Abstract

    Variance components methods that estimate the aggregate contribution of large sets of variants to the heritability of complex traits have yielded important insights into the disease architecture of common diseases. Here, we introduce new methods that estimate the total variance in trait...read more

    Mentioned in this Paper

    BAT Loci
    Single Nucleotide Polymorphism
    Dysequilibrium Syndrome
    Genetic Linkage
    Genome
    28
    204

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