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Contrasting the genetic architecture of 30 complex traits from summary association data

bioRxiv

Jan 4, 2016

Huwenbo ShiBogdan Pasaniuc

Abstract

Variance components methods that estimate the aggregate contribution of large sets of variants to the heritability of complex traits have yielded important insights into the disease architecture of common diseases. Here, we introduce new methods that estimate the total variance in trait...read more

Mentioned in this Paper

Genome-Wide Association Study
Genome
Dysequilibrium Syndrome
Contrast Used
Local
Locus
EAF2
Single Nucleotide Polymorphism
Genetic Linkage
Genetic Loci
28
34
Paper Details
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Contrasting the genetic architecture of 30 complex traits from summary association data

bioRxiv

Jan 4, 2016

Huwenbo ShiBogdan Pasaniuc

PMID: 990035907

DOI: 10.1101/035907

Abstract

Variance components methods that estimate the aggregate contribution of large sets of variants to the heritability of complex traits have yielded important insights into the disease architecture of common diseases. Here, we introduce new methods that estimate the total variance in trait...read more

Mentioned in this Paper

Genome-Wide Association Study
Genome
Dysequilibrium Syndrome
Contrast Used
Local
Locus
EAF2
Single Nucleotide Polymorphism
Genetic Linkage
Genetic Loci
28
34

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Related Papers

American Journal of Human Genetics

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

American Journal of Human GeneticsJune 28, 2016
Huwenbo ShiBogdan Pasaniuc
American Journal of Human Genetics

GCTA: a tool for genome-wide complex trait analysis

American Journal of Human GeneticsDecember 21, 2010
Jian YangPeter M Visscher
Paper Details
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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