Contribution of arterial blood pressure to the clinical expression of lacunar infarction

Stroke; a Journal of Cerebral Circulation
A ChamorroJesús Pujol

Abstract

The relation between symptomatic lacunar infarction, silent stroke, and arterial hypertension is controversial. From 500 patients with ischemic or hemorrhagic stroke admitted to the Downtown Barcelona Stroke Registry between July 1992 and December 1994, we evaluated prospectively the prevalence of silent infarction in 249 patients who had a brain MRI. The association of risk factors with silent infarction was investigated with the use of logistic regression analysis. In a selected group of 43 patients with symptomatic lacunes, we performed at stroke follow-up transcranial Doppler sonography and 24-hour continuous blood pressure monitoring to evaluate whether blood pressure, cerebrovascular tone, and cerebral blood flow at rest and after the administration of 1 g acetazolamide correlated with silent infarction. A total of 147 silent infarctions were observed in 83 patients (33%). Most silent infarctions corresponded to small deep lesions in the territory of the lenticulostriate arteries. Patients with silent infarctions had higher systolic and diastolic blood pressure at stroke onset. However, on multivariate analysis, age greater than 60 years was the only risk factor associated with silent infarction. In a subgroup of 43 patie...Continue Reading

References

Jan 1, 1992·Neurology·C K LiuD F Benson
Feb 1, 1990·Archives of Neurology·C JunquéJ L Marti-Vilalta
Aug 1, 1988·Hypertension·G L Baumbach, D D Heistad
Nov 1, 1988·Neurology·E H ChodoshJ G Furtado
Feb 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·J van Gijn, C L Kraaijeveld

❮ Previous
Next ❯

Citations

Sep 24, 2004·Diabetes/metabolism Research and Reviews·Tsukasa NakamuraHikaru Koide
Sep 5, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·H NakaneM Fujishima
Mar 21, 2002·Acta Neurologica Scandinavica·J Martí-FàbregasJ L Martí-Vilalta
Feb 13, 2009·Expert Review of Neurotherapeutics·Adrià Arboix, Josep Lluís Martí-Vilalta
Apr 2, 2010·Journal of the Neurological Sciences·Seung-Hun OhOk-Joon Kim
Nov 3, 2012·Neurobiology of Aging·Natalie M ZahrAdolf Pfefferbaum
Oct 25, 2002·Cardiovascular Drug Reviews·Katsufumi MizushigeHitoshi Suzuki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

Cerebrovascular Diseases
V FraixJ Perret
Cerebrovascular Diseases
Adrià ArboixCecilia Targa
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Keiji SuzukiMasamitu Takatama
© 2021 Meta ULC. All rights reserved