Contribution of force feedback to ankle extensor activity in decerebrate walking cats

Journal of Neurophysiology
J M Donelan, K G Pearson

Abstract

Previous investigations have demonstrated that feedback from ankle extensor group Ib afferents, arising from force-sensitive Golgi tendon organs, contributes to ankle extensor activity during the stance phase of walking in the cat. The objective of this investigation was to gain insight into the magnitude of this contribution by determining the loop gain of the positive force feedback pathway. Loop gain is the relative contribution of force feedback to total muscle activity and force. In decerebrate cats, the isolated medial gastrocnemius muscle (MG) was held at different lengths during sequences of rhythmic contractions associated with walking in the other three legs. We found that MG muscle activity and force increased at longer muscle lengths. A number of observations indicated that this length dependence was not due to feedback from muscle spindles. In particular, activity in group Ia afferents was insensitive to changes in muscle length during the MG bursts, and electrical stimulation of group II afferents had no influence on the magnitude of burst activity in other ankle extensors. We concluded that the homonymous positive force feedback pathway was isolated from other afferent pathways, allowing the use of a simple model...Continue Reading

References

May 12, 1978·Brain Research·S Grillner, S Rossignol
Jan 1, 1987·Experimental Brain Research·B A ConwayO Kiehn
May 1, 1966·The Journal of Physiology·A M GordonF J Julian
Jan 1, 1995·Experimental Brain Research·P J WhelanK G Pearson
Jan 1, 1994·Experimental Brain Research·J P GossardH Hultborn
Feb 1, 1994·Journal of Neurophysiology·M A GorassiniM J Gauthier
Jun 1, 1997·Journal of Neurophysiology·A ProchazkaD J Bennett
Apr 4, 1998·The Journal of Physiology·A Prochazka, M Gorassini
Mar 16, 2000·The Journal of Physiology·T SinkjaerJ B Nielsen
Jun 16, 2000·The Journal of Physiology·R B SteinK G Pearson
Jul 19, 2000·Gait & Posture·V Dietz, J Duysens
Sep 11, 2003·The Journal of Experimental Biology·Motoshi KayaWalter Herzog
Oct 17, 2003·Proceedings. Biological Sciences·Hartmut GeyerReinhard Blickhan
Nov 4, 2004·Canadian Journal of Physiology and Pharmacology·J Maxwell Donelan, Keir G Pearson

❮ Previous
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Citations

Jan 20, 2006·Experimental Brain Research·Amy Parkinson, Martin McDonagh
Jul 24, 2008·Biological cybernetics·Nalin Harischandra, Orjan Ekeberg
Dec 7, 2006·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Holk CruseJosef Schmitz
Aug 31, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Serge Rossignol
Oct 27, 2012·Journal of Neurophysiology·Dinant A KistemakerPaul L Gribble
Mar 24, 2012·Journal of Neurophysiology·Heather Brant HayesShawn Hochman
Nov 14, 2008·Journal of Neurophysiology·Kyla T Ross, T Richard Nichols
Feb 6, 2009·Journal of Neurophysiology·Keith E GordonBrian D Schmit
Aug 21, 2013·Journal of Neuroengineering and Rehabilitation·Brian K HillenRanu Jung
Jan 20, 2007·The Journal of Experimental Biology·M A DaleyA A Biewener
Jul 20, 2012·The Journal of Experimental Biology·Emma F Hodson-ToleBoris I Prilutsky
Oct 13, 2006·Proceedings of the National Academy of Sciences of the United States of America·Monica A Daley, Andrew A Biewener
Apr 28, 2006·Experimental Brain Research·Nazarena MazzaroThomas Sinkjaer
Sep 14, 2010·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Neil J CroninThomas Sinkjaer
Jan 2, 2007·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·K P Granata, E Rogers
Mar 28, 2013·Annals of the New York Academy of Sciences·Shawn HochmanYoung-Hui Chang
Jul 25, 2014·PLoS Computational Biology·Hugo Gravato MarquesFumiya Iida
Oct 11, 2007·Progress in Brain Research·David A McCrea, Ilya A Rybak
Dec 8, 2017·Journal of Neurophysiology·T Richard Nichols
Mar 25, 2018·The Journal of Physiology·Jakob LorentzenJens Bo Nielsen
Dec 13, 2017·Frontiers in Computational Neuroscience·Christian Schumacher, André Seyfarth
Nov 23, 2006·Biological cybernetics·Alain Frigon, Serge Rossignol
Dec 24, 2005·Physiological Reviews·Serge RossignolJean-Pierre Gossard
Aug 31, 2012·Journal of Neurophysiology·Kathrin HatzJ Maxwell Donelan
Jul 17, 2019·Experimental Brain Research·Aiko K ThompsonJ B Andersen
Sep 26, 2019·Journal of Neurophysiology·Joscha SchmitzAnsgar Büschges
Sep 21, 2019·The Journal of Experimental Biology·David B BoermaSharon M Swartz
Jun 30, 2015·Bioinspiration & Biomimetics·Thomas BuschmannAnsgar Büschges
Jan 4, 2020·Motor Control·Aviroop Dutt-MazumderAiko K Thompson
Jul 7, 2012·Journal of Neural Engineering·Theresa J Klein, M Anthony Lewis
Jan 24, 2009·Journal of Neurophysiology·Richard Af KlintMichael J Grey
Jun 2, 2017·Journal of Neurophysiology·Arthur Prochazka
Nov 12, 2019·Frontiers in Neurorobotics·Volker DürrAxel Schneider
Sep 24, 2005·Journal of Applied Physiology·Daniel P FerrisCatherine R Kinnaird

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