Contribution of geometric design parameters to knee implant performance: Conflicting impact of conformity on kinematics and contact mechanics

The Knee
Marzieh M ArdestaniZhongmin Jin

Abstract

Articular geometry of knee implant has a competing impact on kinematics and contact mechanics of total knee arthroplasty (TKA) such that geometry with lower contact pressure will impose more constraints on knee kinematics. The geometric parameters that may cause this competing effect have not been well understood. This study aimed to quantify the underlying relationships between implant geometry as input and its performance metrics as output. Parametric dimensions of a fixed-bearing cruciate retaining implant were randomized to generate a number of perturbed implant geometries. Performance metrics (i.e., maximum contact pressure, anterior-posterior range of motion [A-P ROM] and internal-external range of motion [I-E ROM]) of each randomized design were calculated using finite element analysis. The relative contributions of individual geometric variables to the performance metrics were then determined in terms of sensitivity indices (SI). The femoral and tibial distal or posterior radii and femoral frontal radius are the key parameters. In the sagittal plane, distal curvature of the femoral and tibial influenced both contact pressure, i.e., SI=0.57; SI=0.65, and A-P ROM, i.e., SI=0.58; SI=0.6, respectively. However, posterior cu...Continue Reading

References

Mar 1, 1994·Journal of Biomechanics·S Sathasivam, P S Walker
Jan 1, 1997·Journal of Biomechanics·P S WalkerJ P Paul
Mar 27, 1999·Journal of Biomechanics·S Sathasivam, P S Walker
Dec 16, 2004·Journal of Biomechanics·Jason P HalloranPaul J Rullkoetter
Sep 28, 2005·Journal of Biomechanics·Peter J LazPaul J Rullkoetter
Sep 28, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Peter J LazPaul J Rullkoetter
Nov 7, 2006·Computer Methods and Programs in Biomedicine·Sarah K EasleyPeter J Laz
Nov 26, 2009·Medical Engineering & Physics·Rebecca BryanPrasanth B Nair
Apr 8, 2010·Journal of Biomechanical Engineering·Benjamin J FreglyJohn D DesJardins
Mar 4, 2011·Journal of Biomechanics·Ryan Willing, Il Yong Kim
Oct 28, 2011·Journal of Biomechanics·Francis GallowayMark Taylor
May 10, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Clare K FitzpatrickPaul J Rullkoetter
Jun 15, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Clare K FitzpatrickPaul J Rullkoetter
Jun 26, 2012·Journal of Biomechanics·Clare K FitzpatrickPaul J Rullkoetter
Nov 13, 2012·The Journal of Arthroplasty·Scott T LovaldSteve M Kurtz
Jan 3, 2015·Medical Engineering & Physics·Marzieh M ArdestaniZhongmin Jin

❮ Previous
Next ❯

Citations

Jul 6, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Yong-Gon KohKyoung-Tak Kang
Dec 19, 2017·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Claire L BrockettLouise M Jennings
Aug 26, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Linjie Wang, Chang Jiang Wang
Nov 23, 2019·Journal of Clinical Medicine·Yong-Gon KohKyoung-Tak Kang
Apr 4, 2020·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Joseph T LynchDiana M Perriman
Jun 29, 2017·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Tilman PfitznerGeorg N Duda
Mar 7, 2021·Journal of Biomechanics·Malte AsselnKlaus Radermacher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.