Contribution of Midparental BMI and other determinants of obesity in adult offspring

Obesity
Niveen M E Abu-RmeilehG C M Watt

Abstract

The aim of this study was to evaluate midparental BMI among intergenerational factors associated with obesity in adult offspring. The data was from an unusual two-generational observational design of 1,477 married couples from Renfrew and Paisley in Scotland who were aged 45-64 years when screened in 1972-1976, and 1,040 sons and 1,298 daughters aged 30-59 years when screened in 1996. BMI was categorized as normal (< 25 kg/m(2)), overweight (25-29.9 kg/m(2)), and obese (> or = 30 kg/m(2)) in offspring and parents. Midparental BMI was defined as the mean of the mother's and father's BMI. Low physical activity, nonsmoking status, higher cholesterol level, and manual social class were all associated with increased BMI in offspring. The effect of reported dietary intake was less clear. Offspring of obese parents (defined by midparental BMI) were over four times more likely to be obese than offspring of normal weight parents. Midparental BMI had a strong effect on offspring BMI, independent of social class, smoking habit, physical activity, and reported dietary intake. Adding midparental BMI to the regression model more than doubled the explained variation of offspring BMI from 7.7 to 17%. Every 1 kg/m(2) increment in midparental BM...Continue Reading

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Citations

May 20, 2011·International Journal of Epidemiology·Rachel M FreathyMarcus Munafò
Jun 16, 2011·Annals of Human Biology·Chris PowerElina Hyppönen
Jul 23, 2013·Journal of the Academy of Nutrition and Dietetics·Leigh Ellen R LasterTruls Østbye
Jul 10, 2013·Obesity·Caroline S FoxRalph B D'Agostino
May 11, 2013·Journal of Epidemiology and Community Health·Kirsti L VikTom I L Nilsen
Jan 12, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M E J Lean
Dec 13, 2019·PloS One·Martha M Téllez-RojoAlejandra Cantoral
Dec 22, 2011·European Journal of Epidemiology·Paul C D JohnsonGraham Watt
Aug 1, 2015·The American Journal of Clinical Nutrition·Louise J FangupoRachael W Taylor

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