Contribution of molecular biology and Aspergillus galactomannan antigen assay for the diagnosis of histoplasmosis

Médecine et maladies infectieuses
S PineauF Raffi

Abstract

We report a case of a pulmonary histoplasmosis in an HIV-positive patient usually living in Cambodia, with a positive Aspergillus galactomannan antigenemia resulting from a cross-reaction, that decreased after antifungal therapy. We discuss the potential interest of the detection of fungal DNA by PCR and Aspergillus galactomannan antigenemia for the diagnosis of histoplasmosis, especially in countries where Histoplasma capsulatum antigen testing is not available.

References

Oct 15, 2003·Trends in Microbiology·L Joseph Wheat
Jan 16, 2007·Clinical Microbiology Reviews·Carol A Kauffman
Mar 9, 2007·Clinical and Vaccine Immunology : CVI·L Joseph WheatChadi Hage
Sep 18, 2007·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S RanqueF Dromer
Jan 15, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L J Wheat, T J Walsh
Jul 3, 2008·Current Opinion in Infectious Diseases·Carol A Kauffman

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Citations

Dec 22, 2019·Journal of Fungi·Izadora Clezar da Silva VasconcellosAlessandro C Pasqualotto
Feb 11, 2020·Mycopathologia·Nida AshrafNathan C Bahr

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