Contribution of PTSD/POW history to behavioral disturbances in dementia

International Journal of Geriatric Psychiatry
S VermaD Hale

Abstract

As many World War II and Korean Conflict veterans suffering from posttraumatic stress disorder (PTSD) grow older, increasing numbers will be diagnosed with dementia. We retrospectively analyzed patients with dementia, comparing the behavioral disturbances of those with PTSD to those without PTSD. We hypothesized that due to the additive effect of the neurobiological and behavioral changes associated with PTSD and dementia, the dementia with PTSD group would show more agitation and disinhibition than the dementia without PTSD group. Sixteen patients with diagnoses of dementia and PTSD were matched on age and Mini-Mental States Examination (MMSE) scores to 16 patients with dementia without PTSD. Demographic characteristics, co-morbid diagnoses, global Assessment of Functioning (GAF), Cohen-Mansfield Agitation Inventory (CMAI), and paranoid items of Brief Psychiatric Rating Scale (BPRS) and Positive and Negative Syndrome Scale for Schizophrenia (PANSS) were assessed. The patients with diagnoses of dementia with PTSD did not differ significantly in their clinical presentation, hospital course, and condition at discharge from patients with dementia without PTSD. Chi-square analysis showed that significantly more subjects in the PTSD...Continue Reading

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Citations

Sep 14, 2007·The Clinical Neuropsychologist·Manfred F Greiffenstein, W John Baker
Mar 27, 2012·The American Journal of Geriatric Pharmacotherapy·Michael L Wolff
Apr 22, 2009·International Journal of Geriatric Psychiatry·Valdesha L BallMark E Kunik
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Feb 20, 2021·Journal of Geriatric Psychiatry and Neurology·Abigail KramerStacy Wilkins
May 11, 2021·European Journal of Psychotraumatology·Sjacko SobczakKay Deckers

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