Abstract
Medication errors and renal impairment contribute to severe adverse drug events, which may lead to hospital admission. To determine whether medication errors and renal impairment contribute to hospital admission and examine these errors for strategies to prevent admissions. The 714 medication-related hospital admissions reported in the prospective multicenter study HARM (Hospital Admissions Related to Medication) were analyzed. The patients were divided into 3 groups based on the availability of creatinine levels: group A, the home-monitored group (n = 227); group B, the hospital-monitored group (n = 420); and group C, the unmonitored group (n = 67). After assessment, 70 admissions (10%) were considered to be related to a medication error and renal impairment (A, 29; B, 41; C, none). In these 70 patients, 85 errors occurred in group A, 66 errors in group B, and none in group C. Dosing errors were identified in 46 patients (A, 14; B, 32), a drug-drug interaction in 22 patients (A, 13; B, 9), and a drug-disease interaction in 17 patients (A, 10; B, 7). Renal impairment and medication errors may lead to medication-related hospital admissions. Monitoring renal function and adjusting pharmacotherapy according to renal function might...Continue Reading
References
Oct 1, 1973·Annals of Internal Medicine·R W Jelliffe
Sep 1, 1980·The American Journal of Psychiatry·R B StewartJ E Adams
Jan 22, 1997·JAMA : the Journal of the American Medical Association·D C ClassenJ P Burke
Jan 22, 1997·JAMA : the Journal of the American Medical Association·T S LesarD S Stein
Jan 1, 1997·Journal of Clinical Epidemiology·J F Steiner, A V Prochazka
Nov 4, 1998·Postgraduate Medical Journal·N A Wong, H W Jones
Nov 18, 2000·Journal of the American Geriatrics Society·A PapaioannouM Bédard
May 1, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·L DuncanA Levin
Jun 26, 2001·Journal of General Internal Medicine·A D FalconnierM Martin-Facklam
Sep 26, 2001·The American Journal of the Medical Sciences·K T HuF T Stevenson
Dec 12, 2001·JAMA : the Journal of the American Medical Association·G M ChertowD W Bates
Aug 28, 2002·The Annals of Pharmacotherapy·Patrick J McDonnell, Michael R Jacobs
Dec 25, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Josef CoreshAndrew S Levey
Jun 24, 2003·Journal of the American Society of Nephrology : JASN·Steven J ChadbanRobert C Atkins
Aug 22, 2003·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·L SalomonP Ravaud
Apr 27, 2005·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Ira S NashMark R Chassin
Jun 29, 2006·The Annals of Pharmacotherapy·Elisabeth A van DijkPeter A G M De Smet
Mar 27, 2007·Journal of Clinical Pharmacy and Therapeutics·J IndermitteK E Hersberger
Nov 8, 2007·JAMA : the Journal of the American Medical Association·Josef CoreshAndrew S Levey
Mar 15, 2008·Pharmacoepidemiology and Drug Safety·Jasperien E van DoormaalFlora M Haaijer-Ruskamp
Apr 15, 2008·BMC Public Health·Qiu-Li Zhang, Dietrich Rothenbacher
Apr 14, 2009·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Theresa HahnPhilip L McCarthy
Apr 25, 2009·Journal of the American Medical Informatics Association : JAMIA·Terry S FieldJerry H Gurwitz
Jul 21, 2009·Archives of Gerontology and Geriatrics·Liu XunLou Tanqi
Aug 7, 2009·Drugs & Aging·Anders HelldénGunnar Ohlén
Aug 20, 2009·The Annals of Pharmacotherapy·Maarten J ten BergWouter W van Solinge
Sep 18, 2009·Kidney International·Balthasar L HugDavid W Bates
Sep 25, 2009·The Annals of Pharmacotherapy·Yahaya HassanRozina Ghazali
Dec 10, 2009·JAMA : the Journal of the American Medical Association·Thomas T TsaiUNKNOWN National Cardiovascular Data Registry
Feb 8, 2011·Theriogenology·J MustersA C Okkens
Apr 1, 2011·Pharmacotherapy·Bharati BhardwajaDavid J Magid
Citations
Jun 3, 2014·The Journal of Ambulatory Care Management·Richard BernsteinArlen Collins
Jul 9, 2014·Journal of General Internal Medicine·Michael A SteinmanJanice B Schwartz
Jan 1, 2012·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Fabio SalviAntonio Cherubini
Oct 28, 2015·Journal of the American Geriatrics Society·Flora ChangMichael A Steinman
Jul 3, 2013·Journal of Clinical Pharmacy and Therapeutics·A F J GeertsW W van Solinge
Apr 25, 2015·Journal of Evaluation in Clinical Practice·Thibaut CarubaBrigitte Sabatier
Jul 8, 2015·BMC Nephrology·Willemijn L EppengaRob J Van Marum
Mar 6, 2015·PloS One·Willemijn L EppengaPeter A G M De Smet
Jun 17, 2016·International Journal of Clinical Pharmacy·Ellen S KosterMarcel L Bouvy
Jul 2, 2016·PloS One·Ahsan Saleem, Imran Masood
Oct 8, 2017·The Annals of Pharmacotherapy·Eline HoubenPeter A G M de Smet
Nov 10, 2017·Drugs & Aging·Mette HeringaMarcel L Bouvy
Feb 28, 2019·BMJ : British Medical Journal·David Oliver
Feb 21, 2019·BMJ : British Medical Journal·David Oliver
Aug 29, 2016·European Journal of Clinical Pharmacology·Willemijn L EppengaPeter A G M De Smet
Mar 7, 2018·Drugs & Aging·Abdul Aziz Al WazzanKoen Boussery
Jul 25, 2018·Drugs & Aging·Alex SecoraMorgan E Grams
Sep 4, 2018·Applied Health Economics and Health Policy·Judith J Gout-ZwartMaarten J Postma
Oct 30, 2020·European Journal of Hospital Pharmacy. Science and Practice·Mesut SancarBetul Okuyan
Sep 7, 2021·Drugs & Aging·Lisa M Kalisch EllettElizabeth E Roughead