Contribution of Socioeconomic Status to Racial/Ethnic Disparities in Adverse Pregnancy Outcomes Among Women With Systemic Lupus Erythematosus

Arthritis Care & Research
Elianna T KaplowitzJane E Salmon


We examined rates of adverse pregnancy outcomes (APO) by race/ethnicity among women with systemic lupus erythematosus (SLE), with and without antiphospholipid antibodies (aPL), and whether socioeconomic status (SES) accounted for differences. Data were from the PROMISSE (Predictors of Pregnancy Outcome: Biomarkers in Antiphospholipid Antibody Syndrome and Systemic Lupus Erythematosus) study, a multicenter study that enrolled 346 patients with SLE and 62 patients with SLE and aPL (50% white, 20% African American, 17% Hispanic, 12% Asian/Pacific Islander). Measures of SES were educational attainment, median community income, and community education. Logistic regression analyses were conducted to determine odds of APO for each racial/ethnic group, controlling first for age and clinical variables, and then for SES. The frequency of APO in white women with SLE, with and without aPL, was 29% and 11%, respectively. For African American and Hispanic women it was approximately 2-fold greater. In African American women with SLE alone, adjustment for clinical variables attenuated the odds ratio (OR) from 2.7 (95% confidence interval [95% CI] 1.3-5.5) to 2.3 (95% CI 1.1-5.1), and after additional adjustment for SES, there were no longer si...Continue Reading


Jan 1, 1990·Indian Journal of Pathology & Microbiology·N JayaramS Sehgal
Dec 1, 1987·Arthritis and Rheumatism·S StudenskiR P Polisson
Sep 1, 1995·Arthritis and Rheumatism·D J McCartyC K Kwoh
Dec 1, 1996·Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association·T M WatersR Ramsey-Goldman
May 1, 1998·International Journal of Epidemiology·J Sundquist, S E Johansson
Oct 2, 2004·Obstetrics and Gynecology·Bo JacobssonIan Milsom
May 3, 2005·Obstetrics and Gynecology·Jane Cleary-GoldmanUNKNOWN FASTER Consortium
Feb 22, 2011·Best Practice & Research. Clinical Obstetrics & Gynaecology·Jennifer A HutcheonK S Joseph
Mar 20, 2015·Journal of Perinatology : Official Journal of the California Perinatal Association·A E B BordersW Grobman
Jun 23, 2015·Annals of Internal Medicine·Jill P BuyonJane E Salmon
Jan 28, 2016·Arthritis Care & Research·Megan E B Clowse, Chad Grotegut
Aug 26, 2016·Nature Reviews. Rheumatology·Erin E CarterAnn E Clarke
Nov 21, 2016·American Journal of Obstetrics and Gynecology·Christopher W JonesStacy S Drury

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