Contribution of TRPV channels to osmosensory transduction, thirst, and vasopressin release

Kidney International
Reza Sharif-NaeiniC W Bourque

Abstract

Systemic osmoregulation is an integrated physiological process through which water intake and excretion are continuously balanced against salt intake and excretion to maintain the osmolality of the extracellular fluid near an optimal 'set-point' value. The behaviors (that is, thirst and sodium appetite) and renal responses (diuresis and natriuresis) that are modulated to mediate osmoregulatory homeostasis are mainly controlled by the nervous system. Appropriate regulation of these parameters depends in large part on specialized osmosensitive neurons, termed osmoreceptors, which convert changes in plasma osmolality into electrical signals that ultimately modulate effector functions to achieve homeostasis. Previous work has shown that mechanosensitive cation channels expressed in osmoreceptor neurons play a key role in the process of osmosensory transduction. Although the molecular identity of these channels remains unknown, a growing body of evidence, reviewed here, indicates that members of the transient receptor potential vanilloid family of ion channels may contribute to osmosensory transduction and to homeostatic responses implicated in the control of water balance.

References

Sep 1, 1978·Brain Research Bulletin·G I HattonW A Gregory
Nov 1, 1974·Physiology & Behavior·J K Walters, G I Hatton
Dec 1, 1973·The Journal of Clinical Investigation·F L DunnG L Robertson
Sep 1, 1994·Frontiers in Neuroendocrinology·C W BourqueD Richard
Jun 5, 2003·American Journal of Physiology. Cell Physiology·Atsuko MizunoMakoto Suzuki
Sep 27, 2003·Circulation Research·Katsuhiko MurakiYuji Imaizumi
Oct 29, 2003·Proceedings of the National Academy of Sciences of the United States of America·Wolfgang Liedtke, Jeffrey M Friedman
Oct 29, 2003·Proceedings of the National Academy of Sciences of the United States of America·Wolfgang LiedtkeJeffrey M Friedman
Dec 23, 2003·Best Practice & Research. Clinical Endocrinology & Metabolism·Joseph G Verbalis
Dec 6, 2005·Nature Neuroscience·Reza Sharif NaeiniCharles W Bourque
Feb 8, 2006·Annual Review of Physiology·I Scott RamseyDavid E Clapham
May 23, 2006·Seminars in Nephrology·Michael J McKinleyMichael L Mathai
Sep 1, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sorana Ciura, Charles W Bourque
Apr 13, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Zizhen ZhangCharles W Bourque
Dec 16, 1947·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·E B VERNEY

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Citations

Dec 8, 2010·The Journal of Biological Chemistry·Julia BarsonyJoseph G Verbalis
Oct 27, 2011·Current Opinion in Critical Care·Milap Pokaharel, Clay A Block
Jun 6, 2013·Current Opinion in Nephrology and Hypertension·Olivier Devuyst, Vicente E Torres
Oct 22, 2009·Clinical and Experimental Pharmacology & Physiology·Peter Bie, Mads Damkjaer
Aug 19, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Annie M WhitakerPatricia E Molina
Jan 5, 2011·Nephron. Physiology·Reinout M SwartRobert Zietse
May 13, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Daniel A RyskampDavid Krizaj
Feb 4, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Andras GaramiAndrej A Romanovsky
May 18, 2010·Hospital Practice·Robert D ZenenbergMark A Merlin
Apr 26, 2012·The Journal of Physiology·Charles W BourqueWolfgang Liedtke
Jul 4, 2012·Experimental Neurology·Thekkethil Prashant NedungadiJ Thomas Cunningham
Nov 1, 2011·General and Comparative Endocrinology·A P SealeE G Grau
Feb 9, 2010·Neuroscience Letters·Ayano NagakuraMasaharu Noda
Aug 7, 2010·Congestive Heart Failure·Mitchell H Rosner, Claudio Ronco
Jun 4, 2014·Pflügers Archiv : European journal of physiology·Jinfeng TengChing Kung
Mar 5, 2015·PloS One·Feiteng Ji, Yan Zhu
Oct 19, 2016·Naunyn-Schmiedeberg's Archives of Pharmacology·Puneet Kaur Randhawa, Amteshwar Singh Jaggi
Nov 26, 2016·Acta Clinica Belgica·Fabrice Gankam Kengne
Dec 14, 2016·IEEE Transactions on Bio-medical Engineering·Nan XiaClaus-Peter Richter
Aug 1, 2014·Clinical Journal of the American Society of Nephrology : CJASN·John Danziger, Mark L Zeidel
Jul 26, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Celia D Sladek, Alan Kim Johnson
Nov 7, 2018·Neurophotonics·Yingyue XuClaus-Peter Richter
May 6, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Taro Watanabe, Yoshio Takei
Dec 11, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Jack RubinsteinJohn N Lorenz
Nov 14, 2017·Nature Reviews. Nephrology·Claire Gizowski, Charles W Bourque
Aug 18, 2010·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Mark L Zeidel
Dec 29, 2020·Progress in Biophysics and Molecular Biology·Yingyue XuClaus-Peter Richter
Oct 16, 2020·Nature·Allan-Hermann PoolYuki Oka
Apr 20, 2021·Laryngoscope Investigative Otolaryngology·Philip D Littlefield, Claus-Peter Richter

❮ Previous
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