Contributions and challenges for worldwide vaccine safety: The Global Advisory Committee on Vaccine Safety at 15 years

Vaccine
Edwin J AsturiasPatrick L F Zuber

Abstract

In 1999, the Global Advisory Committee on Vaccine Safety (GACVS) was established by the World Health Organization (WHO) to provide independent scientific advice on issues relating to the safety of vaccines and immunization. Fifteen years onward, we conducted a multi-faceted review to evaluate the impact, reach and challenges facing GACVS, including the role GACVS plays in informing global, regional and WHO member state vaccine policy. The methods included measures of organizational structure, citation impact, themes approached, and a discussion by previous and current members to evaluate past, present and future challenges. Given the increasing range of data sources and the deployment of many new vaccines, the Committee is facing the complex task of identifying the best available evidence for recommendations on vaccine safety. To help meet the increased demand for public transparency in decision making, GACVS-structured methodology for evidence-based decisions is evolving. GACVS also promotes best practices and capacity building for timely and accurate risk assessment; risk communications; outreach to help countries maintain and, if needed, rebuild public trust in vaccines; and advocacy for bridging the major gaps in vaccine sa...Continue Reading

References

Jul 15, 1999·JAMA : the Journal of the American Medical Association·D A SalmonR T Chen
Nov 24, 1999·Vaccine·R T Chen
Feb 24, 2001·The New England Journal of Medicine·T V MurphyRotavirus Intussusception Investigation Team
May 4, 2004·Vaccine·P Duclos
Oct 30, 2004·American Journal of Public Health·Peter I FolbOmala Wimalaratne
Aug 10, 2005·The Journal of Infectious Diseases·L SimonsenA Z Kapikian
Feb 16, 2006·The Journal of Infectious Diseases·Kenneth J RothmanFelix Arellano
Oct 28, 2008·Vaccine·Marta Martínez-MoraFrancisco Rodríguez-Salvanés
Feb 11, 2011·Human Vaccines·Nicola P Klein
Aug 9, 2011·Vaccine·Leonoor WijnansMiriam Sturkenboom
Aug 16, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Sylwia BujkiewiczAlex J Sutton

Citations

Sep 11, 2007·Infectious Disease Clinics of North America·Victoria E PriceE Lee Ford-Jones
Sep 5, 2015·Infectious Disease Clinics of North America·Penelope H Dennehy
Nov 2, 2019·Expert Review of Vaccines·Jianlin ZhuangQingwu Jiang
Sep 3, 2019·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Alexandru BarboiAmerican Autonomic Society
Dec 14, 2019·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Svetlana Blitshteyn
Aug 3, 2019·British Journal of Clinical Pharmacology·Bruce M McClenathan, Kathryn M Edwards
Dec 21, 2018·Revista Do Instituto De Medicina Tropical De São Paulo·Vera Lúcia GattásAlexander Roberto Precioso

Related Concepts

Product Approval
National Health Policy
Vaccines
World Health Organization
Review Committees
Decision Making
Equipment Safety
Research Methodology
Risk Assessment
Evaluation

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