Contributions of blood pressure to proteinuria and renal function in the puerperium

Blood Pressure
Xiaowei LiuGuoshuang Xu

Abstract

Increasing evidence indicates that hypertension in pregnancy plays a key role in cardiovascular disease. However, the correlation between blood pressure (BP) and proteinuria as well as renal function in the puerperium has not been established. We evaluated the estimated glomerular filtration rate (eGFR) and 24-h urine total protein excretion (TPE) during the second postpartum week in 852 pregnant women with normal BPs and 114 pre-eclamptic women with BPs > or =140/90 mmHg. The 852 pregnant women with normal BPs were divided into two groups based on the mean arterial pressure (MAP): 684 subjects with an MAP<90 mmHg and 168 subjects with an MAP> or =90 mmHg. The eGFR was significantly decreased in pre-eclamptic women (112+/-41 ml/min/1.73 m(2)) compared with healthy women with an MAP<90 mmHg (131+/-35 ml/min/1.73 m(2), p<0.01) and an MAP> or =90 mmHg (128+/-34 ml/min/1.73 m(2), p<0.01), while the TPE was significantly increased compared with healthy women with an MAP<90 mmHg and an MAP> or =90 mmHg (1790+/-1422 vs 124+/-148 and 255+/-427 mg/24 h, respectively; p<0.001). Although the eGFR did not reveal a difference between the two groups of healthy women (131+/-35 vs 128+/-34 ml/min/1.73 m(2), p>0.05), the TPE was significantly h...Continue Reading

References

Mar 31, 1990·BMJ : British Medical Journal·J MartinellG Lidin-Janson
Jun 1, 1993·British Journal of Obstetrics and Gynaecology·P G Whittaker, T Lind
Oct 10, 1998·Kidney International·R A LafayetteB D Myers
Jul 15, 1999·Journal of the American Society of Nephrology : JASN·R A LafayetteB D Myers
Dec 12, 2001·American Journal of Physiology. Renal Physiology·J E C MilneJ M Davison
Feb 22, 2003·Journal of the American Society of Nephrology : JASN·Paul MoranJohn M Davison
Nov 13, 2003·American Journal of Physiology. Renal Physiology·M A HladunewichB D Myers
Mar 4, 2005·BMJ : British Medical Journal·Kirsten Duckitt, Deborah Harrington
Nov 3, 2005·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Kok-Min SeowDa-Chung Chen
Oct 13, 2006·Journal of the American Society of Nephrology : JASN·Mauro AbbateGiuseppe Remuzzi
Jul 10, 2007·The Journal of Clinical Hypertension·Steven J WagnerVesna D Garovic
Oct 25, 2007·Nature Clinical Practice. Nephrology·Vesna D Garovic, Suzanne R Hayman

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Citations

Jan 22, 2013·Wiener klinische Wochenschrift·Selman UnverdiMurat Duranay

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