Contributions of Retinal Ganglion Cells to Subcortical Visual Processing and Behaviors

Annual Review of Vision Science
Onkar S DhandeAndrew D Huberman

Abstract

Every aspect of visual perception and behavior is built from the neural activity of retinal ganglion cells (RGCs), the output neurons of the eye. Here, we review progress toward understanding the many types of RGCs that communicate visual signals to the brain, along with the subcortical brain regions that use those signals to build and respond to representations of the outside world. We emphasize recent progress in the use of mouse genetics, viral circuit tracing, and behavioral psychophysics to define and map the various RGCs and their associated networks. We also address questions about the homology of RGC types in mice and other species including nonhuman primates and humans. Finally, we propose a framework for understanding RGC typology and for highlighting the relationship between RGC type-specific circuitry and the processing stations in the brain that support and give rise to the perception of sight.

References

Jan 1, 1979·Annual Review of Neuroscience·R W Rodieck
Apr 1, 1975·The Journal of Comparative Neurology·U C Dräger
Jan 1, 1976·Journal of Neurophysiology·U C Dräger, D H Hubel
Oct 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·D M Dacey, M R Petersen
Apr 1, 1989·Trends in Neurosciences·P DeanG W Westby
Nov 15, 1989·The Journal of Comparative Neurology·M Watanabe, R W Rodieck
Jan 1, 1988·Experimental Brain Research·D P NorthmoreG E Schneider
Jan 1, 1987·Annual Review of Neuroscience·J Nathans
Jan 1, 1987·Annual Review of Neuroscience·E I KnudsenS D Esterly
Mar 1, 1985·The Journal of Comparative Neurology·R W RodieckJ Dineen
Apr 22, 1985·The Journal of Comparative Neurology·A Hofbauer, U C Dräger
Jul 1, 1974·The Journal of Physiology·B B Boycott, H Wässle
Sep 14, 1973·Science·D Ingle
Dec 15, 1974·The Journal of Comparative Neurology·T P Langer, R D Lund
Mar 1, 1968·The Journal of Physiology·D H Hubel, T N Wiesel
Jan 1, 1969·Journal of Neurophysiology·B G Wickelgren, P Sterling
Sep 1, 1965·Journal of Neurophysiology·R W Rodieck, J Stone
Jan 1, 1984·Annual Review of Neuroscience·J I Simpson
Aug 1, 1983·Brain Research·R Linden, V H Perry
Jan 1, 1980·Annual Review of Neuroscience·R H Wurtz, J E Albano
Sep 1, 1980·The Journal of Comparative Neurology·N J Mangini, A L Pearlman
Aug 1, 1982·The Journal of Physiology·W R Levick, L N Thibos
May 1, 1994·Journal of Neurophysiology·S A Bloomfield

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Citations

May 5, 2017·The Journal of Comparative Neurology·Luis Pérez de Sevilla MüllerNicholas C Brecha
Feb 24, 2017·Neuron·Benjamin K Stafford, Andrew D Huberman
Apr 12, 2018·Journal of Neurophysiology·William Guido
Jun 9, 2018·The European Journal of Neuroscience·Y Kate HongChinfei Chen
Feb 10, 2018·ELife·Aboozar MonavarfeshaniMichael A Fox
Jun 1, 2018·Annual Review of Vision Science·Jianhua CangXiaorong Liu
Jun 2, 2018·Annual Review of Vision Science·Jens Kremkow, Jose-Manuel Alonso
Apr 21, 2018·The Journal of Comparative Neurology·Rana N El-Danaf, Andrew D Huberman
Aug 5, 2017·Annual Review of Neuroscience·Tania A SeabrookAndrew D Huberman
Jan 16, 2020·International Journal of Molecular Sciences·Kim Tuyen Nguyen-Ba-Charvet, Alexandra Rebsam
Apr 2, 2020·International Journal of Molecular Sciences·María Constanza PotilinskiJuan Eduardo Gallo
Dec 31, 2019·Experimental and Therapeutic Medicine·Yadan QuanMinbin Yu
Sep 17, 2020·Annual Review of Vision Science·Liang Liang, Chinfei Chen
May 2, 2017·Annual Review of Neuroscience·Chi ZhangRebecca E James
Nov 24, 2015·Annual Review of Vision Science·Jonathan B Demb, Joshua H Singer
Jun 29, 2018·Frontiers in Immunology·Ghanshyam Swarup, Zuberwasim Sayyad
Apr 9, 2020·Wiley Interdisciplinary Reviews. Developmental Biology·Hannah K Graham, Xin Duan
Jul 12, 2016·Nature Neuroscience·Jung-Hwan A LimAndrew D Huberman
Jan 18, 2017·The Journal of Comparative Neurology·Subha Nasir-AhmadUlrike Grünert
Dec 3, 2016·Developmental Neurobiology·Delphine S Prieur, Alexandra Rebsam
Oct 3, 2017·Visual Neuroscience·Daniel Kerschensteiner, William Guido
Jun 2, 2020·Frontiers in Cellular Neuroscience·Shu-Guang YangFeng-Quan Zhou
Apr 2, 2020·Frontiers in Computational Neuroscience·Michael J Berry, Gašper Tkačik
Dec 9, 2020·Development·Shane D'Souza, Richard A Lang
Jan 5, 2021·ELife·Masahito YamagataJoshua R Sanes
Jul 6, 2016·Current Opinion in Neurobiology·Ryan D Morrie, Marla B Feller
Oct 20, 2018·Current Opinion in Neurobiology·Supraja G Varadarajan, Andrew D Huberman
Apr 3, 2021·Current Biology : CB·Fei WangYifeng Zhang
Mar 31, 2021·Neuron·Keith P JohnsonDaniel Kerschensteiner
Apr 8, 2020·Current Biology : CB·Alyssa M Rivera, Andrew D Huberman
Jun 13, 2021·Developmental Biology·Natalie R HamiltonAlex L Kolodkin
Jul 7, 2021·Annual Review of Vision Science·Karthik Shekhar, Joshua R Sanes
Oct 17, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jianmin SuMichael A Fox
Nov 8, 2021·The Journal of Comparative Neurology·Shane P D'SouzaRichard A Lang
Jan 6, 2022·Science China. Life Sciences·Wei XiaoXiao-Hong Xu

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Methods Mentioned

BETA
transgenic
dissection
imaging techniques

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