PMID: 9190024Dec 1, 1996Paper

Control of avian mycoplasmoses by vaccination

Revue Scientifique Et Technique
K G Whithear

Abstract

Vaccination is an option for controlling Mycoplasma gallisepticum or M. synoviae when biosecurity measures fail to prevent the infection of poultry flocks with these mycoplasmas. Both killed vaccines (bacterins) and living vaccines are currently in commercial use. Bacterins usually contain an oil emulsion adjuvant and are administered by subcutaneous or intramuscular injection. They can reduce the decline in egg production associated with M. gallisepticum, although they do not prevent infection. Newer adjuvants, such as immune stimulating complexes, may provide effective immunity without the tissue lesions caused by oil emulsion adjuvants. Living M. gallisepticum vaccines include the F strain and attenuated strains ts-11 and 6/85. F strain is administered in drinking water or by aerosol. This strain reduces the decline in egg production and has been used to displace endemic strains in multiple-age flocks. The major disadvantage is the inherent virulence of F strain. Strain ts-11 is less virulent and less infectious than F strain and provides a somewhat weaker, but usually effective, long-term protective immunity, which is vaccine-dose dependent. This strain is administered by eye drop, persists in the chicken for long periods a...Continue Reading

Citations

Feb 2, 2006·Avian Pathology : Journal of the W.V.P.A·A FeberweeJ A Stegeman
Oct 23, 2008·Avian Diseases·S H Kleven
Aug 4, 2012·Avian Diseases·N Ferguson-NoelS H Kleven
Jan 13, 2015·Avian Pathology : Journal of the W.V.P.A·N M Ferguson-Noel, S M Williams
Dec 24, 2019·Avian Diseases·Mostafa Ghanem, Mohamed El-Gazzar
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