PMID: 8593404Sep 1, 1995Paper

Control of Brucella melitensis infection in a large camel herd in Saudi Arabia using antibiotherapy and vaccination with Rev. 1 vaccine

Revue Scientifique Et Technique
A I RadwanE R Coloyan

Abstract

The authors describe an attempt to control Brucella melitensis infection in a large camel herd in Saudi Arabia. Sera from the entire herd (2,536) were examined by the Rose Bengal and standard United States of America buffered plate agglutination tests. The overall Brucella seroprevalence was 8%. Milk samples from the 120 seropositive milking camels were cultured on Brucella-selective media. B. melitensis biovars 1, 2 and 3 were isolated from 41 camels (34%). Seropositive camels (202) were treated for the first time with a combination of long-acting oxytetracycline (OTC) at a dose of 25 mg/kg administered intramuscularly (i.m.) every 2 days for 30 days and streptomycin at 25 mg/kg i.m. every 2 days for 16 days. In addition, milking camels were given OTC-intramammary infusion at a rate of 10 ml/teat every 2 days for 8 days. This regimen was found to be effective in eliminating the shedding of Brucella organisms by camels, with no relapse. Moreover, all treated camels became seronegative within 16 months after treatment. Seronegative camels (2,331) were vaccinated for the first time with the B. melitensis Rev. 1 strain vaccine, as follows: a) 175 young camels (aged three months to one year) were each inoculated subcutaneously with...Continue Reading

Citations

May 17, 2008·Tropical Animal Health and Production·Ahmad M Al-MajaliOdea F Al-Rawashdeh
Jun 5, 2013·Frontiers in Biology·Xinghong YangDavid W Pascual
Dec 24, 2005·Expert Review of Vaccines·Steven C Olsen, W S Stoffregen
Dec 26, 2012·Pathogens and Global Health·Lisa D SpragueHeinrich Neubauer
May 22, 2009·Tropical Animal Health and Production·Yasser M GhanemYasin A Musse
Jan 31, 2018·Frontiers in Microbiology·Jeffrey T FosterMuhammad Saqib
Sep 27, 2002·Preventive Veterinary Medicine·B Abbas, H Agab
Nov 5, 2002·Veterinary Microbiology·Mohamed Refai
Mar 19, 2008·Journal of Comparative Pathology·M T MusaL Perrett

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