PMID: 11607097Sep 1, 1990Paper

Control of expression of Agrobacterium vir genes by synergistic actions of phenolic signal molecules and monosaccharides

Proceedings of the National Academy of Sciences of the United States of America
N ShimodaY Machida

Abstract

Most virulence (vir) genes of Agrobacterium tumefaciens that are required for the formation of crown gall tumors are expressed in response to such plant signal molecules as acetosyringone and lignin precursors. The phenolic signals are transduced through a receptor VirA protein in the inner membrane of the bacterial cell. The expression of these genes triggers the transfer of a specific DNA segment, called transferred DNA (T-DNA), from the Ti plasmid to plant cells, and its integration into their nuclear DNA. We show here that a group of aldoses (L-arabinose, D-xylose, D-lyxose, D-glucose, D-mannose, D-idose, D-galactose, and D-talose) can markedly enhance acetosyringone-dependent expression of vir genes when the concentration of acetosyringone is limited (10 microM) but does not enhance the expression of noninducible genes. Likewise, a 2-deoxy-D-glucose, a nonmetabolized sugar, is also effective. When a deletion was introduced into the virA gene in the region encoding the periplasmic portion of the VirA protein, enhancement by glucose disappeared, but vir expression was induced by acetosyringone in this mutant. These results suggest that these sugars directly enhance a signaling process initiated by phenolic inducers that resu...Continue Reading

References

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Citations

Apr 5, 2002·Chembiochem : a European Journal of Chemical Biology·Yulei WangDavid G Lynn
May 1, 1992·Plant Molecular Biology·P J Hooykaas, R A Schilperoort
Jul 1, 1996·World Journal of Microbiology & Biotechnology·K Weising, G Kahl
Aug 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·G J PazourA Das
Sep 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·K M HessA N Binns
Sep 12, 1995·Proceedings of the National Academy of Sciences of the United States of America·S UsamiY Machida
May 20, 2006·Annual Review of Cell and Developmental Biology·Colleen A McCullen, Andrew N Binns
Dec 21, 2012·Future Microbiology·Rebekka Steinmann, Petra Dersch
Oct 1, 1992·Molecular & General Genetics : MGG·P de PhilipP Boistard
Aug 12, 2000·Molecular Plant-microbe Interactions : MPMI·L Nachin, F Barras
Oct 5, 2010·Plant Signaling & Behavior·Adi ZaltsmanVitaly Citovsky
Jan 23, 2015·Frontiers in Plant Science·Eugene W Nester
Mar 17, 2018·Molecular Plant-microbe Interactions : MPMI·Guirong TangLi Luo
Mar 1, 1993·Molecular Microbiology·S C TurkP J Hooykaas
Aug 1, 1991·Molecular & General Genetics : MGG·S OkamotoY Machida
Jun 19, 2007·Journal of Bacteriology·Rong Gao, David G Lynn
Mar 5, 2004·Journal of Bacteriology·Avanti BaruahMichiko M Nakano
Dec 13, 2006·Microbiology and Molecular Biology Reviews : MMBR·Thorsten MascherGottfried Unden
Jun 29, 2016·PloS One·Ramachandran Srinivasan, Kodiveri Muthukalianan Gothandam
Jun 16, 2016·Acta Crystallographica. Section F, Structural Biology Communications·Umesh YadavaSteven C Almo
Oct 28, 2017·Molecular Microbiology·Lauren M Sheehan, Clayton C Caswell
Feb 1, 1995·Molecular Microbiology·K M Ottemann, J J Mekalanos
Dec 1, 2015·Journal, Genetic Engineering & Biotechnology·Mallesham BulleSadanandam Abbagani

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