PMID: 374888Jan 1, 1979Paper

Control of immunologic abnormalities associated with aging

Mechanisms of Ageing and Development
T MAKINODAN

Abstract

In an attempt to encourage more intensive studies on the control of immunologic abnormalities associated with aging, the six different approaches which have been attempted are reviewed briefly. They are as follows: (a) internal body temperature control, (b) tissue ablation, (c) dietary manipulation, (d) genetic manipulation, (d) genetic manipulation (e) cell therapy and (f) chemical therapy. The first four are preventive and the latter two are restorative in approach. Many of these studies are very preliminary, but overall, the findings are most encouraging. These studies should resolve the extent to which decline in immunologic vigor with age influences the disease pattern of aging individuals and on their life expectancy.

References

Nov 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·R G Cutler
Mar 1, 1977·Mechanisms of Ageing and Development·G E Bilder, W D Denckla
Nov 2, 1976·The Journal of Experimental Medicine·J W Albright, T Makinodan
Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·G FernandesR A Good
Jan 9, 1975·The New England Journal of Medicine·D W WaraA J Ammann
Feb 28, 1975·Annals of the New York Academy of Sciences·N TalalR Goldblum
Mar 1, 1975·Journal of Gerontology·R K Liu, R L Walford
Jan 1, 1973·International Archives of Allergy and Applied Immunology·G FernandesR A Good
Jan 11, 1969·Lancet·D MazzeiV Simonati
Dec 29, 1972·Nature·N FabrisE Sorkin
Mar 1, 1968·Biochemical Pharmacology·E V Barnett
Apr 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·G FernandesR A Good
Apr 30, 1971·Annals of the New York Academy of Sciences·W LandsW Smith
Jun 1, 1966·Journal of Cellular Physiology·J F Albright, T Makinodan
Jan 15, 1967·International Journal of Cancer. Journal International Du Cancer·D Metcalf, R Moulds
Feb 1, 1974·The Journal of Clinical Investigation·W D Denckla
Feb 1, 1962·Proceedings of the National Academy of Sciences of the United States of America·T MAKINODAN, W J PETERSON

❮ Previous
Next ❯

Citations

Jul 1, 1983·Journal of Steroid Biochemistry·C J Grossman, G A Roselle
Mar 1, 1981·Clinics in Endocrinology and Metabolism·M Green
Jan 1, 1983·Journal of Chronic Diseases·K W Walton
May 1, 1986·Veterinary Pathology·C F KuperV M Hollanders

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.