Control of konzo in DRC using the wetting method on cassava flour

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
J P BaneaN Kuwa

Abstract

Fifty konzo cases were identified in four villages in Popokabaka Health Zone, DRC. One third of people had only one meal per day, mainly of cassava flour consumed as a thick porridge (fufu) and pounded, boiled cassava leaves. Retention of cyanogens in flour resulted from short soaking of cassava roots. A 1.5 years intervention was made in the largest village Kay Kalenge, where the wetting method was taught to all women of the village, who accepted it willingly. The total cyanide content of cassava flour was reduced to below 10 ppm. Fufu from treated flour tasted and stored better than fufu from untreated flour. The mean urinary thiocyanate content of 100 school children reduced from 332 to 130 μmole/L and the number of samples exceeding 350 μmole/L decreased from 26 to 0 during the intervention. No new konzo cases occurred, which included two dry seasons when konzo peaks. Konzo was first identified by Dr. Trolli in 1938 in Popokabaka Health Zone and it has now been prevented for the first time in the same area. The methodology is now in use in Boko Health Zone and we believe it is the most effective way to control konzo in tropical Africa.

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Citations

Aug 4, 2012·PLoS Neglected Tropical Diseases·Delphin Diasolua NgudiFernand Lambein
Aug 15, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J P BaneaD Tshala Katumbay
Jul 4, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Bola Adamolekun
Aug 16, 2013·International Journal of Food Sciences and Nutrition·O S A Oluwole, A O Oludiran
Mar 5, 2020·Neurology·Omar K SiddiqiElizabeth Chizema-Kawesha
May 9, 2021·The American Journal of Clinical Nutrition·Merry C FitzpatrickDaniel G Maxwell
May 20, 2021·Seminars in Neurology·Michaël C C Slama, Aaron L Berkowitz

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