Control of leaf vascular patterning by polar auxin transport.

Genes & Development
Enrico ScarpellaThomas Berleth

Abstract

The formation of the leaf vascular pattern has fascinated biologists for centuries. In the early leaf primordium, complex networks of procambial cells emerge from homogeneous subepidermal tissue. The molecular nature of the underlying positional information is unknown, but various lines of evidence implicate gradually restricted transport routes of the plant hormone auxin in defining sites of procambium formation. Here we show that a crucial member of the AtPIN family of auxin-efflux-associated proteins, AtPIN1, is expressed prior to pre-procambial and procambial cell fate markers in domains that become restricted toward sites of procambium formation. Subcellular AtPIN1 polarity indicates that auxin is directed to distinct "convergence points" in the epidermis, from where it defines the positions of major veins. Integrated polarities in all emerging veins indicate auxin drainage toward pre-existing veins, but veins display divergent polarities as they become connected at both ends. Auxin application and transport inhibition reveal that convergence point positioning and AtPIN1 expression domain dynamics are self-organizing, auxin-transport-dependent processes. We derive a model for self-regulated, reiterative patterning of all v...Continue Reading

References

Nov 24, 1999·The Plant Cell·F M CarlandB Keith
Apr 13, 2000·The Plant Cell·D ReinhardtC Kuhlemeier
Jul 1, 1997·The Plant Cell·T. Nelson, N. Dengler
Aug 2, 2003·Science·José M AlonsoJoseph R Ecker
Nov 25, 2003·Nature·Didier ReinhardtCris Kuhlemeier
Nov 27, 2004·Trends in Plant Science·Eric M Kramer
Nov 22, 2005·The Plant Journal : for Cell and Molecular Biology·Anne-Gaëlle Rolland-Lagan, Przemyslaw Prusinkiewicz
Apr 8, 2006·Science·Justyna WisniewskaJirí Friml
Jan 1, 2003·The Arabidopsis Book·Simon Turner, Leslie E Sieburth

❮ Previous
Next ❯

Citations

Sep 27, 2012·Journal of Mathematical Biology·Delphine DraelantsWim Vanroose
Mar 28, 2013·Plant Cell Reports·Ana Milhinhos, Célia M Miguel
Sep 29, 2009·Journal of Plant Research·Sandra K Floyd, John L Bowman
Oct 13, 2009·Journal of Plant Research·Claudia CanalesMiltos Tsiantis
Jul 26, 2008·Plant Molecular Biology·Jan DettmerYkä Helariutta
Mar 3, 2011·Nature Reviews. Molecular Cell Biology·Adrienne H K RoederElliot M Meyerowitz
Mar 24, 2011·Nature Reviews. Molecular Cell Biology·Malgorzata A Domagalska, Ottoline Leyser
Mar 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Pankaj DhonuksheJirí Friml
Nov 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Jürgen Kleine-VehnJirí Friml
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Marta IbañesAna I Caño-Delgado
Dec 8, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jürgen Kleine-VehnJirí Friml
Feb 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Gemma D BilsboroughMiltos Tsiantis
Nov 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Abel RosadoNatasha V Raikhel
Nov 19, 2010·The Journal of Biological Chemistry·Etsuko TsudaKen-ichiro Hayashi
May 27, 2010·Journal of Experimental Botany·Petra Stamm, Prakash P Kumar
Aug 13, 2010·Journal of Experimental Botany·Kathleen HectorsKris Vissenberg
May 15, 2013·Journal of Experimental Botany·Michael SauerJürgen Kleine-Vehn
Dec 1, 2006·Plant & Cell Physiology·Hélène BaubyJean-Christophe Palauqui
Jun 6, 2009·Plant & Cell Physiology·Makoto ShirakawaIkuko Hara-Nishimura
May 24, 2012·Plant & Cell Physiology·Jian Bo SongZhi Min Yang
Nov 7, 2012·Plant & Cell Physiology·Thomas L SlewinskiRobert Turgeon
Jan 30, 2013·Plant & Cell Physiology·Kyoko Ohashi-ItoHiroo Fukuda
May 11, 2010·Cold Spring Harbor Perspectives in Biology·Teva VernouxJan Traas
Feb 26, 2010·Cold Spring Harbor Perspectives in Biology·Enrico ScarpellaMiltos Tsiantis
Mar 20, 2010·Cold Spring Harbor Perspectives in Biology·Eva ZazímalováPetr Hosek
Feb 26, 2010·Cold Spring Harbor Perspectives in Biology·Pawel Krupinski, Henrik Jönsson
Oct 18, 2006·Genes & Development·Michael SauerEva Benková
Jul 5, 2011·Genes & Development·Saiko YoshidaCris Kuhlemeier
Mar 21, 2007·Plant Physiology·Jalean Joyanne Petricka, Timothy Mark Nelson
Jun 9, 2007·Plant Physiology·Tim J BrodribbGregory J Jordan
Aug 8, 2008·Plant Physiology·Mathias SchuetzJim Mattsson
Jun 14, 2008·Plant Physiology·Andrea GallavottiDavid Jackson
Aug 6, 2008·Plant Physiology·Elena Feraru, Jirí Friml

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.