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Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin

Journal of Cellular Physiology

Jan 1, 1976

A Y Tourian

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Abstract

Stationary-phase, minimal deviation hepatoma H4-II-E-C3 cell cultures that are serum-deprived respond with a biphasic time course of phenylalanine hydroxylase induction when dialyzed fetal calf serum or insulin is added. These two agents induce phenylalanine hydroxylase additively, duri...read more

Mentioned in this Paper

Liver Neoplasms
Ac-De
Protein Biosynthesis
Enzyme Induction
Cattle calf (organism)
Uridine
Cycloheximide
RNA
Tyrosine Aminotransferase
Tissue Culture
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  • Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin

    Journal of Cellular Physiology

    Jan 1, 1976

    A Y Tourian

    PMID: 1401

    DOI: 10.1002/jcp.1040870104

    Abstract

    Stationary-phase, minimal deviation hepatoma H4-II-E-C3 cell cultures that are serum-deprived respond with a biphasic time course of phenylalanine hydroxylase induction when dialyzed fetal calf serum or insulin is added. These two agents induce phenylalanine hydroxylase additively, duri...read more

    Mentioned in this Paper

    Liver Neoplasms
    Ac-De
    Protein Biosynthesis
    Enzyme Induction
    Cattle calf (organism)

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