Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless

Science
S Grimm, G O Pflugfelder

Abstract

Diffusible factors of several protein families control appendage outgrowth and patterning in both insects and vertebrates. In Drosophila wing development, the gene decapentaplegic (dpp) is expressed along the anteroposterior compartment boundary. Early wingless (wg) expression is involved in setting up the dorsoventral boundary. Interaction between dpp- and wg-expressing cells promotes appendage outgrowth. Here, it is shown that optomotor-blind (omb) expression is required for distal wing development and is controlled by both dpp and wg. Ectopic omb expression can lead to the growth of additional wings. Thus, omb is essential for wing development and is controlled by two signaling pathways.

References

Mar 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·J A KassisN Perrimon
Feb 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·G O PflugfelderM Heisenberg
Mar 1, 1995·Comparative Biochemistry and Physiology. Part A, Physiology·G O Pflugfelder, M Heisenberg
Apr 1, 1995·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·S S Blair
Sep 1, 1994·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·H Meinhardt
Jan 22, 1993·Science·P J Bryant
Jan 22, 1993·Science·J P CousoA Martínez-Arias
May 1, 1994·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Lewis I HeldScott D Peters

❮ Previous
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Citations

Mar 21, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·V E Papaioannou, L M Silver
Aug 1, 1997·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·C Neumann, S Cohen
Dec 8, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Timothy F Plageman, Katherine E Yutzey
Dec 25, 2009·Molecular Genetics and Genomics : MGG·Aditya SenGert O Pflugfelder
Oct 1, 1998·Behavioural Brain Research·G O Pflugfelder
Mar 1, 1997·Cytokine & Growth Factor Reviews·R W PadgettP Das
Nov 15, 2002·Developmental Cell·Jeremy J Gibson-Brown
Jan 1, 1997·Nature Genetics·M J Dixon
May 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Jaime ResinoAntonio García-Bellido
Mar 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·Litty PaulAmanda Simcox
Sep 23, 2003·Proceedings of the National Academy of Sciences of the United States of America·Elisa C WoodhouseLance A Liotta
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·S F TsaiY H Sun
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·M l HeY Rao
Jul 10, 1999·Genes & Development·R Diez del CorralJ Modolell
Dec 24, 2010·Genome Research·Lucy CherbasPeter Cherbas
Apr 11, 2000·Molecular and Cellular Biology·Y TakatsuN Ueno
Nov 21, 2002·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Arun Mehra, Jeffrey L Wrana
Oct 14, 2000·Annual Review of Cell and Developmental Biology·R S Mann, G Morata
Jan 11, 2008·Development·Carlos Estella, Richard S Mann
Aug 29, 2006·PLoS Biology·Christopher J LoweJohn Gerhart
Aug 11, 2012·PloS One·Susanne FischerStephan Schneuwly
Dec 6, 1997·Current Opinion in Genetics & Development·M Bienz
Sep 27, 2002·Genesis : the Journal of Genetics and Development·Takashi Adachi-Yamada
Dec 5, 2008·Journal of Neurogenetics·G O Pflugfelder
Sep 3, 2005·Evolution; International Journal of Organic Evolution·Jennifer A BrissonAlan R Templeton
Jan 30, 2015·Evolution & Development·Ralf JanssenGraham E Budd

❮ Previous
Next ❯

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