PMID: 3756475Aug 13, 1986Paper

Control of the neuronal rhythmic bursts in the septal pacemaker of theta-rhythm: effects of anaesthetic and anticholinergic drugs

Brain Research
E S Brazhnik, O S Vinogradova

Abstract

The drugs, described as blocking the high-frequency (pentobarbital) or low-frequency (scopolamine, atropine) theta rhythm of the hippocampal electroencephalogram, were tested upon the rhythmically bursting septal cells. Three groups of chronic, unanaesthetized rabbits were used for the experiments: with intact septum; with septohippocampal disconnection; with complete basal undercutting of the septum, depriving it of ascending brainstem influences (MFB lesion). While the frequency and other parameters of theta bursts did not differ in the first two groups (5.2-5.5 Hz), in MFB-lesioned septum their frequency was significantly lower (3.5 Hz). Intravenous injection of pentobarbital suppressed theta bursts in some cells with unstable, periodic rhythmic activity and lowered the frequency of the bursts in continuously bursting cells. The parameters of bursts in intact and hippocampectomized septum under pentobarbital did not differ from those of undercut septum in undrugged state. Acetylcholine-blocking drugs suppressed theta modulation in some intermittently bursting cells, but only slightly decreased regularity of the bursts in some cells with continuous theta bursting even in sublethal doses; physostigmine has the opposite effect....Continue Reading

References

Mar 1, 1977·Electroencephalography and Clinical Neurophysiology·I Q Whishaw, T Schallert
Sep 1, 1979·Experimental Brain Research·J N RawlinsJ A Gray
Apr 6, 1979·Brain Research·P AndersenP A Schwartzkroin
Jan 1, 1978·Neuroscience·N McNaughton, E M Sedgwick
Feb 28, 1985·Neuroscience Letters·B H WainerE J Mufson
Apr 1, 1969·Electroencephalography and Clinical Neurophysiology·C H Vanderwolf
Jan 4, 1974·Brain Research·R B ChronisterL E White
May 1, 1974·Journal of Comparative and Physiological Psychology·T E Robinson, I Q Whishaw
Aug 1, 1967·Brain Research·G GogolákC Stumpf
Nov 1, 1980·Electroencephalography and Clinical Neurophysiology·T E Robinson, D J Green
Oct 1, 1981·Electroencephalography and Clinical Neurophysiology·C L Faingold, W E Hoffmann
Apr 1, 1983·Electroencephalography and Clinical Neurophysiology·J HolsheimerF H Lopes da Silva
Oct 1, 1984·Physiology & Behavior·R S Sainsbury, C P Montoya
Jan 1, 1982·Experimental Brain Research·J Holsheimer
May 5, 1980·Brain Research·S J Mitchell, J B Ranck
Apr 14, 1980·Brain Research·O S VinogradovaS D Zhadina
Jul 1, 1965·Electroencephalography and Clinical Neurophysiology·H PETSCHEP A VANZWIETEN

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Citations

Jan 1, 1995·Hippocampus·G BuzsákiJ J Chrobak
Jan 1, 1987·Neir̆ofiziologiia = Neurophysiology·O S VinogradovaE S Brazhnik
Jan 1, 1989·Neuroscience and Behavioral Physiology·E S Brazhnik, O S Vinogradova
Nov 1, 1993·Neuroscience and Behavioral Physiology·E S BrazhnikV F Kichigina
May 1, 1989·Neuroscience and Behavioral Physiology·E S Brazhnik, O S Vinogradova
Sep 1, 1990·Neuroscience and Behavioral Physiology·A B Belousov, O S Vinogradova
Sep 1, 1989·Neuroscience and Behavioral Physiology·V F Kichigina, O S Vinogradova
Nov 1, 1995·Neuroscience and Behavioral Physiology·O S VinogradovaV F Kichigina
Nov 1, 1996·Neuroscience and Behavioral Physiology·V F Kichigina, T A Gordeeva
Jan 1, 1996·Neuroscience and Behavioral Physiology·O S VinogradovaV F Kichigina
Nov 13, 1989·Brain Research·V F Kitchigina, O S Vinogradova
Aug 1, 1993·Progress in Neurobiology·B H Bland, L V Colom
Jul 8, 1991·Neuroscience Letters·B H LeeM H Bassant
Dec 1, 1988·Neuroscience·M H BassantY Lamour
Jun 1, 1989·Brain Research Bulletin·C GottesmannB Zernicki
Sep 23, 1997·Pharmacology, Biochemistry, and Behavior·P MonmaurM M'Harzi
Jun 26, 1999·The European Journal of Neuroscience·D S AlbeckA Granholm
Jul 1, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marian TsanovShane M O'Mara
Jun 28, 2005·The European Journal of Neuroscience·Gábor NyíriTamás F Freund
Jul 5, 2006·The European Journal of Neuroscience·A NuñezV Teruel
Jan 18, 2005·Behavioral and Cognitive Neuroscience Reviews·Robert P VertesGonzalo Viana Di Prisco
Aug 9, 2017·PloS One·Ali Hummos, Satish S Nair

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