Control strategy with multivariable fault tolerance module for automatic intravenous anesthesia.

Biomedical Engineering Letters
Bhavina PatelAlpesh Sarvaia

Abstract

In the anesthesia automation, an automatic propofol infusion system uses Bi-spectral Index Signal (BIS) as a primary feedback signal to manipulate propofol dose. However, the BIS signal may be suspended for some time due to poor EEG signal quality, noise, and many other factors. Therefore, BIS signal failure may be the main cause of inadequate propofol infusion. This fact motivates the need for integration of multivariable fault tolerance module (MFTM) and fractional-order Smith predictor controller to avoid adverse reactions of inadequate propofol dosing during BIS failure. Smith Predictor control strategy is sufficiently robust to predict feedback BIS during BIS failure via patient pharmacological modeled BIS. However, modeled BIS may not provide a guarantee of adequate propofol infusion during BIS failure and especially in the presence of hypotension and hypertension. Thus, the proposed control strategy is designed with MFTM to detect BIS sensor fault and to estimate feedback BIS during BIS failure. Further, the proposed control strategy is designed with a multivariable pharmacological patient model to analyze the cross effect of propofol infusion on BIS and hemodynamic variables. The robustness of the proposed control strat...Continue Reading

References

Mar 17, 2000·Anesthesiology·J Schüttler, H Ihmsen
Mar 13, 2008·IEEE Transactions on Bio-medical Engineering·Yoshihito SawaguchiKazhuiko Fukuda
May 2, 2009·Computer Methods in Biomechanics and Biomedical Engineering·Juan Albino MéndezHéctor Reboso
Oct 21, 2010·IEEE Transactions on Bio-medical Engineering·Clara M IonescuRobin De Keyser
Feb 9, 2011·The AAPS Journal·Martin BergstrandMats O Karlsson
Nov 5, 2014·Korean journal of anesthesiology·Sang Wook LeeYoung Kyoo Choi
Nov 6, 2014·IEEE Transactions on Bio-medical Engineering·Ioana NascuEfstratios N Pistikopoulos
Feb 24, 2016·ISA Transactions·Robin De KeyserClara M Ionescu
Jun 14, 2016·Computers in Biology and Medicine·I Martín-MateosJ F Gómez-González
Jan 4, 2017·Revista brasileira de anestesiologia·Muhammad IlyasRaja Ali Riaz
May 13, 2017·Computer Methods and Programs in Biomedicine·Fabrizio PadulaGiulio Vivacqua
Jul 25, 2017·Computer Methods and Programs in Biomedicine·Luca MerigoAntonio Visioli
Jan 10, 2018·Artificial Intelligence in Medicine·Juan Albino MendezJosé F Gomez-Gonzalez
Oct 22, 2018·ISA Transactions·Amélie ChevalierRobin De Keyser
Apr 9, 2019·Biomedical Engineering Letters·Bhavina PatelAlpesh Sarvaia

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

British Journal of Anaesthesia
N H Green
Acta Crystallographica. Section C, Crystal Structure Communications
F J CraigR E Mulvey
Acta Crystallographica. Section C, Crystal Structure Communications
L SuescunR Baggio
Anaesthesia and Intensive Care
A J Davidson
Anesthesiology
Mohammad A Helwani
© 2021 Meta ULC. All rights reserved