Controlled clinical laboratory comparison of BACTEC plus aerobic/F resin medium with BacT/Alert aerobic FAN medium for detection of bacteremia and fungemia.

Journal of Clinical Microbiology
J H JorgensenL Barth Reller

Abstract

Blood specimens collected from adult patients with suspected sepsis in four medical centers were inoculated into BACTEC Plus/F and BacT/Alert FAN aerobic culture bottles. Both bottles of 7,401 bottle pairs contained the prescribed blood volume of 8 to 12 ml. Bottles were incubated in their respective instruments for a standard 7-day protocol or until the instruments signaled that they were positive. A total of 720 isolates that were judged to represent true infections were recovered from 338 patients; 451 isolates were recovered from both bottles, 143 were recovered from only the Plus/F bottle, and 126 were recovered from only the FAN bottle (P was not significant). Although more Histoplasma capsulatum isolates were recovered from Plus/F bottles (P < 0.005), there were no other statistically significant differences in recovery rates of individual species or groups of organisms between the two systems. Of 329 monomicrobic patient septic episodes, 244 episodes were detected by both blood culture systems, 40 were detected only by the BACTEC system, and 45 were detected only by the BacT/Alert system (P was not significant). There was no significant difference between the two systems in the detection of septic episodes among patient...Continue Reading

References

Feb 1, 1992·Journal of Clinical Microbiology·M L WilsonL B Reller
Jan 1, 1992·Journal of Clinical Microbiology·M L WilsonL B Reller
May 1, 1991·Journal of Clinical Microbiology·M P WeinsteinL B Reller
Jul 1, 1990·Journal of Clinical Microbiology·T C ThorpeL B Reller
Jun 1, 1988·American Journal of Infection Control·J S GarnerJ M Hughes
Jan 1, 1983·Journal of Clinical Microbiology·P C AppelbaumL L Stone
Jul 1, 1995·Journal of Clinical Microbiology·J A SmithF J Roberts
Jul 1, 1993·Diagnostic Microbiology and Infectious Disease·S E SharpR J Poppiti

❮ Previous
Next ❯

Citations

Apr 29, 2006·BMC Infectious Diseases·Galo PeraltaMaría Pía Roiz
Nov 14, 1997·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H LelièvreJ Etienne
Nov 16, 2004·Critical Care Medicine·Jonathan CohenJames Jorgensen
Dec 12, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rebecca ZadrogaGlen T Hansen
Oct 4, 2014·Clinical Microbiology Reviews·Kevin B Laupland, Deirdre L Church
Oct 22, 2013·BMC Infectious Diseases·Cintia Zoya NunesCarlos Alberto Pires Pereira
Jun 17, 2016·Journal of Clinical Microbiology·Aaron CampigottoChristopher D Doern
May 8, 2020·The Pediatric Infectious Disease Journal·Michael W KuzniewiczKaren M Puopolo
Sep 19, 2018·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Won-Young KimKwangha Lee
Nov 23, 2020·Seminars in Perinatology·Michael W Kuzniewicz, Karen M Puopolo
Jun 7, 2003·Journal of Clinical Microbiology·Melvin P Weinstein
Jan 13, 2004·Journal of Clinical Microbiology·Lynn L HorvathDuane R Hospenthal
Feb 10, 2004·Journal of Clinical Microbiology·Marie-Hélène MeyerErmanno Candolfi
Nov 18, 1998·Journal of Clinical Microbiology·J SpaargarenG P Voorn
Oct 12, 2016·Microbiology Spectrum·Deirdre L Church
Jun 10, 1998·Journal of Clinical Microbiology·P R MurrayM L Wilson
May 9, 1998·Journal of Clinical Microbiology·R T Waite, G L Woods
Oct 8, 1997·Journal of Clinical Microbiology·P RohnerR Auckenthaler
Feb 20, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Peter Rohner, Raymond Auckenthaler
May 22, 2010·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Stefan Riedel, Karen C Carroll

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.